Modification of the p53 transgene of a replication-competent adenovirus prevents mdm2- and E1b-55kD-mediated degradation of p53.
about
Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapySelectivity and efficiency of late transgene expression by transcriptionally targeted oncolytic adenoviruses are dependent on the transgene insertion strategy.Negative regulation-resistant p53 variant enhances oncolytic adenoviral gene therapy.Mechanisms of apoptosis regulation by viral oncogenes in infection and tumorigenesis.Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded.The mitochondrial p53 pathway.Armed replicating adenoviruses for cancer virotherapy.Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model.Mitochondrially targeted wild-type p53 suppresses growth of mutant p53 lymphomas in vivo.
P2860
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P2860
Modification of the p53 transgene of a replication-competent adenovirus prevents mdm2- and E1b-55kD-mediated degradation of p53.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Modification of the p53 transg ...... D-mediated degradation of p53.
@en
type
label
Modification of the p53 transg ...... D-mediated degradation of p53.
@en
prefLabel
Modification of the p53 transg ...... D-mediated degradation of p53.
@en
P2093
P2860
P356
P1433
P1476
Modification of the p53 transg ...... kD-mediated degradation of p53
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.CGT.7700936
P577
2006-02-10T00:00:00Z
P5875
P6179
1046643323