Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis. - Wikidata - awgldk - TriplyDB

Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.

Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.

http://www.wikidata.org/entity/Q40321378

about

VHL, the story of a tumour suppressor gene.Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome.Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.WSB1 promotes tumor metastasis by inducing pVHL degradation Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma Molecular targets on the horizon for kidney and urothelial cancer.The role of HIF1α in renal cell carcinoma tumorigenesis.Blocking peptides and molecular mimicry as treatment for kidney disease.Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration.Simultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice.Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis.The HIF and other quandaries in VHL disease.Renal Cell Carcinoma in von Hippel-Lindau Disease-From Tumor Genetics to Novel Therapeutic Strategies.

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P2860

Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.

http://www.wikidata.org/entity/Q40321378

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Activation of HIF2α in kidney ...... osition but not tumorigenesis.

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type

label

Activation of HIF2α in kidney ...... osition but not tumorigenesis.

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prefLabel

Activation of HIF2α in kidney ...... osition but not tumorigenesis.

@en

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0008-5472.CAN-12-3983

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Cancer Research

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Activation of HIF2α in kidney ...... osition but not tumorigenesis.

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David M Nanus

http://www.w3.org/2001/XMLSchema#string

Gang Wang

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Leiping Fu

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Lorraine J Gudas

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Maria M Shevchuk

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P2860

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

Fast and accurate short read alignment with Burrows-Wheeler transform

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data

Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

The Ki-67 protein: from the known and the unknown

Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma

The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

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2916-2925

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9

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