about
Partial tolerance of autoreactive B and T cells to erythrocyte-specific self-antigens in mice.Current problems and future directions of transfusion-induced alloimmunization: summary of an NHLBI working group.Regulation of primary alloantibody response through antecedent exposure to a microbial T-cell epitopeShort duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.Generation of transgenic mice with antithetical KEL1 and KEL2 human blood group antigens on red blood cellsComplex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy.Resolution of translation start site for the human Kell glycoprotein.Factors Influencing RBC Alloimmunization: Lessons Learned from Murine Models.Transfusion-induced bone marrow transplant rejection due to minor histocompatibility antigensCTLA4-Ig prevents alloantibody production and BMT rejection in response to platelet transfusions in mice.Alloimmunization against RBC or PLT antigens is independent of TRIM21 expression in a murine modelMetabolomics of ADSOL (AS-1) red blood cell storageRapid clearance of transfused murine red blood cells is associated with recipient cytokine storm and enhanced alloimmunogenicity.Established and theoretical factors to consider in assessing the red cell storage lesionTransfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.Alloimmunization to transfused platelets requires priming of CD4+ T cells in the splenic microenvironment in a murine modelTransfusion in the absence of inflammation induces antigen-specific tolerance to murine RBCs.Identification and characterization of CD8+ suppressor T cells.Analysis of CD8+ T cell-mediated anti-viral responses in mice with targeted deletions of the M1 or M5 muscarinic cholinergic receptors.Frequency of glucose-6-phosphate dehydrogenase-deficient red blood cell units in a metropolitan transfusion service.Storage of murine red blood cells enhances alloantibody responses to an erythroid-specific model antigenThe spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells.Use of mouse models to study the mechanisms and consequences of RBC clearance.Transfusion-transmitted cytomegalovirus: lessons from a murine model.Prevention of transfusion-transmitted cytomegalovirus in low-birth weight infants (≤1500 g) using cytomegalovirus-seronegative and leukoreduced transfusions.Cytokine storm in a mouse model of IgG-mediated hemolytic transfusion reactions.Transfusion of murine red blood cells expressing the human KEL glycoprotein induces clinically significant alloantibodies.Lessons learned from mouse models of hemolytic transfusion reactionsAlloantibodies to a paternally derived RBC KEL antigen lead to hemolytic disease of the fetus/newborn in a murine modelA novel role for C3 in antibody-induced red blood cell clearance and antigen modulation.Blood donation and blood transfusion: special considerations for African Americans.Hypothesis: hemolytic transfusion reactions represent an alternative type of anaphylaxisThe role of inflammation in alloimmunization to antigens on transfused red blood cells.Transfusion of minor histocompatibility antigen-mismatched platelets induces rejection of bone marrow transplants in mice.Initiation and regulation of complement during hemolytic transfusion reactions.Fresh versus old blood: are there differences and do they matter?Pathobiology of transfusion reactions.Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription.Macrophages clear refrigerator storage-damaged red blood cells and subsequently secrete cytokines in vivo, but not in vitro, in a murine model.Alloimmunization to transfused HOD red blood cells is not increased in mice with sickle cell disease.
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
James C Zimring
@ast
James C Zimring
@en
James C Zimring
@es
James C Zimring
@nl
James C Zimring
@sl
type
label
James C Zimring
@ast
James C Zimring
@en
James C Zimring
@es
James C Zimring
@nl
James C Zimring
@sl
prefLabel
James C Zimring
@ast
James C Zimring
@en
James C Zimring
@es
James C Zimring
@nl
James C Zimring
@sl
P106
P21
P31
P496
0000-0002-1063-4010