Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.
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Mouse models of polyglutamine diseases: review and data table. Part IAtaxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse modelThe histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1The first knockin mouse model of episodic ataxia type 2Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1.RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration.Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model.Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7.Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7RNA pathogenesis via Toll-like receptor-activated inflammation in expanded repeat neurodegenerative diseases.Intercellular (mis)communication in neurodegenerative disease.Prion-Like Characteristics of Polyglutamine-Containing Proteins.Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.Polyglutamine spinocerebellar ataxias - from genes to potential treatments.Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
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P2860
Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Spinocerebellar ataxia type 7 ...... us bergmann glia degeneration.
@en
type
label
Spinocerebellar ataxia type 7 ...... us bergmann glia degeneration.
@en
prefLabel
Spinocerebellar ataxia type 7 ...... us bergmann glia degeneration.
@en
P2093
P2860
P1476
Spinocerebellar ataxia type 7 ...... ous bergmann glia degeneration
@en
P2093
Albert R La Spada
Bryce L Sopher
Christopher Chang
Mathini S Mohanachandran
Sarah M Waldherr
Stephanie A Furrer
Vincent A Damian
P2860
P304
16269-16278
P356
10.1523/JNEUROSCI.4000-11.2011
P407
P577
2011-11-01T00:00:00Z