The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux.
about
Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypesStructural and mutational analyses of Drp35 from Staphylococcus aureus: a possible mechanism for its lactonase activityValidation of PON1 enzyme activity assays for longitudinal studiesHuman paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological rolesOne enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activityIn vivo administration of BL-3050: highly stable engineered PON1-HDL complexesTobacco Smoke Exposure Reduces Paraoxonase Activity in a Murine Model.Estradiol enhances cell-associated paraoxonase 1 (PON1) activity in vitro without altering PON1 expression.Association of chemerin with oxidative stress, inflammation and classical adipokines in non-diabetic obese patients.Relationship between the paraoxonase (PON1) L55M and Q192R polymorphisms and obesity in a Mexican population: a pilot studyRelationship between paraoxonase and homocysteine: crossroads of oxidative diseases.Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport.Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein InteractionPomegranate for your cardiovascular healthMyeloperoxidase, paraoxonase-1, and HDL form a functional ternary complexLysophosphatidyl choline modulates mechanosensitive L-type Ca2+ current in circular smooth muscle cells from human jejunum.Serum Protein KNG1, APOC3, and PON1 as Potential Biomarkers for Yin-Deficiency-Heat Syndrome.The Search for Dietary Supplements to Elevate or Activate Circulating Paraoxonases.Indices of paraoxonase and oxidative status do not enhance the prediction of subclinical cardiovascular disease in mixed-ancestry South Africans.Catalytic mechanisms for phosphotriesterasesAssessing the functional properties of high-density lipoproteins: an emerging concept in cardiovascular research.Paraoxonase activity as a marker of exposure to xenobiotics in tobacco smoke.Selective oxidative stress and cholesterol metabolism in lipid-metabolizing cell classes: Distinct regulatory roles for pro-oxidants and antioxidants.HDL3 stimulates paraoxonase 1 antiatherogenic catalytic and biological activities in a macrophage model system: in vivo and in vitro studies.Reduced glutathione increases quercetin stimulatory effects on HDL- or apoA1-mediated cholesterol efflux from J774A.1 macrophages.Monocyte-macrophage membrane possesses free radicals scavenging activity: stimulation by polyphenols or by paraoxonase 1 (PON1).VLDL triglycerides inhibit HDL-associated paraoxonase 1 (PON1) activity: in vitro and in vivo studies.Paraoxonase 1 activities and genetic variation in childhood obesity.Injection of paraoxonase 1 (PON1) to mice stimulates their HDL and macrophage antiatherogenicity.A homogeneous cell-based assay for measurement of endogenous paraoxonase 1 activity.Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes.Increased methionine sulfoxide content of apoA-I in type 1 diabetes.Oxidation hypothesis of atherogenesis: HDL inflammatory index and apolipoprotein A-I mimetic peptides.PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways.A high throughput serum paraoxonase assay for discovery of small molecule modulators of PON1 activity.Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State.Measurement of serum paraoxonase-1 activity in the evaluation of liver function.The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.Potential association of paraoxonase-1, type 2 diabetes mellitus, and periodontitis.Paraoxonase 1 lactonase activity and distribution in the HDL subclasses in the cord blood.
P2860
Q24610194-A77AFD3F-D694-420B-98A0-85C5EDE88A8CQ27643299-E992A386-2D6C-4A6D-BE5E-8581EA022693Q28388799-FCD5294B-9D96-4E16-87D6-A829EB1B3D60Q28395898-A109F7CD-3221-4220-9075-271AA492FA23Q28397498-CE136C0A-42FB-4C2B-BF15-5F4C6557AD3CQ30891417-3F64EFB2-46AC-44D2-AEEF-9F55A5B2CEC0Q33650636-4ACEA9B8-C694-4455-92E4-2C68F303E08AQ33976196-5D802B09-81A8-498E-A3D3-30A178F2C2B6Q34011460-0129D560-20E4-466C-97E5-31F0C358E6B3Q35401516-66B649B5-6245-4782-BD16-FCF35D37DBC1Q35843994-35F68409-CD88-4E73-9A70-F1127140C251Q36302734-F4B4240A-DE07-485D-AE8F-DDBAF0166168Q36489313-BCEC087A-03DE-45A8-B450-4BCFF66E7D6FQ36919245-8D504160-3BFD-4D08-A96E-84BE7F938CF5Q37123887-15A9C262-EE3F-45C5-81FA-F9DAD4EA3BC7Q37162450-3FF07CE8-8B9C-428B-B5A9-D879DB88393CQ37397117-2667DDD5-6B7C-4334-A4F4-5D3FCEA57C33Q37690989-8723E9F7-5052-468B-8950-E1E37D7B4548Q37700886-83109122-ECE4-43D3-967E-11B1C78CA796Q38007798-103B4B45-285D-4CE8-BA93-26E26D684E64Q38111810-EB48CBD8-F610-4CA4-B828-EC0D0537F8D3Q38466473-F517B78C-C85C-4888-9EF9-CEC551A7F6CCQ38847658-244E45D2-130C-4C4E-BBD3-23722EA28E6EQ38955607-62446FA1-3F81-4E65-A274-3EA594F69671Q38958121-65455B7B-C0C8-44CB-973B-DEEB3F2A7B23Q39211143-D5114309-5393-4D3F-9431-DA47C83D57A4Q39335668-8171CF3F-A9BA-4247-9A32-1D9D1011DA9AQ39398869-00E7573D-1445-4D87-8E9F-0D2D04A5CB0CQ39429336-ADCA2E51-BB08-49D0-9720-F05F027F395DQ39748960-3CAF55BA-EF04-43C9-BB1B-807652180B53Q39797833-83C7F15F-333A-4160-95F1-912A2CB23EE5Q40133402-F915312B-C6AD-4360-9E94-3D1CC8247767Q40218716-7AA961F7-07E9-4A1E-AC35-C8756A813815Q40793611-53376AF4-D4E5-4329-948A-29D05BA96B38Q42941287-9F71E368-92C4-4D8D-9AA8-BD9CA2B8E624Q43120971-06FFBE28-EE93-444A-87A4-C67D397C14ACQ43138173-78155CE4-24A5-47DF-B0C7-A4242FD5D5E9Q43235426-216EC4D7-C73B-4995-B521-79139E64B333Q43467302-8EFE8BF9-B988-42A6-B1AA-4323AF6185B8Q43806535-A9433F62-002C-4CEA-AD22-623186813074
P2860
The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The catalytic histidine dyad o ...... macrophage cholesterol efflux.
@en
type
label
The catalytic histidine dyad o ...... macrophage cholesterol efflux.
@en
prefLabel
The catalytic histidine dyad o ...... macrophage cholesterol efflux.
@en
P2093
P2860
P356
P1476
The catalytic histidine dyad o ...... macrophage cholesterol efflux.
@en
P2093
Dan S Tawfik
Jacob Vaya
Leonid Gaidukov
Michael Aviram
Mira Rosenblat
Olga Khersonsky
P2860
P304
P356
10.1074/JBC.M512595200
P407
P577
2006-01-10T00:00:00Z