about
Kinetic models reveal the in vivo mechanisms of mutagenesis in microbes and manCrystallographic studies on damaged DNAs IV. N( 4)-methoxycytosine shows a second face for Watson-Crick base-pairing, leading to purine transition mutagenesisStructure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNAIsolation and characterization of temperature-sensitive mutations in RPA190, the gene encoding the largest subunit of RNA polymerase I from Saccharomyces cerevisiaeHydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agentsAn active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agentsSuicide inactivation of the E. coli O6-methylguanine-DNA methyltransferaseThe effect of induced mutations on quantitative traits in Arabidopsis thaliana: Natural versus artificial conditionsInduction of dnaN and dnaQ gene expression in Escherichia coli by alkylation damage to DNA.Transcription-associated mutagenesis increases protein sequence diversity more effectively than does random mutagenesis in Escherichia coliSite-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine.Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts.DNA repair dependence of somatic mutagenesis of transposon-caused white alleles in Drosophila melanogaster after treatment with alkylating agents.Transcriptional bias: a non-Lamarckian mechanism for substrate-induced mutationsMolecular analysis of O6-substituted guanine-induced mutagenesis of ras oncogenesProtonation preferentially stabilizes minor tautomers of the halouracils: IRMPD action spectroscopy and theoretical studies.Circular dichroism of poly(dG-dC) modified by the carcinogens N-methyl-4-aminoazobenzene or 4-aminobiphenyl.In vivo formation and persistence of modified nucleosides resulting from alkylating agents.Computer-assisted mechanistic structure-activity studies: application to diverse classes of chemical carcinogens.Mechanisms of genotoxin-induced transcription and hypermutation in p53.The roles of transcription and genotoxins underlying p53 mutagenesis in vivo.Adaptive response of Micrococcus luteus to alkylating chemicals.Detection and identification of mutagens and carcinogens as their adducts with guanosine derivatives.Base pairing involving deoxyinosine: implications for probe design.Chemical adaptation of M. luteus induces repair functions for O-alkylated DNA pyrimidines.A theoretical evaluation of the effect of netropsin binding on the reactivity of DNA towards alkylating agents.A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N'-methylurea.Mutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data.Identification of an amber nonsense mutation in the rosy516 gene by germline transformation of an amber suppressor tRNA geneStructural studies of O6-methyldeoxyguanosine and related compounds: a promutagenic DNA lesion by methylating carcinogens.Mutational alterations of translational coupling in the L11 ribosomal protein operon of Escherichia coliConstruction and characterization of extrachromosomal probes for mutagenesis by carcinogens: site-specific incorporation of O6-methylguanine into viral and plasmid genomes.Adaptive response in mammalian cells: crossreactivity of different pretreatments on cytotoxicity as contrasted to mutagenicity.Regioselective arylation of ribose in adenosine and guanosine with the antitumor drug N2-methyl-9-hydroxyellipticinium acetate.Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems.Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells.Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors.The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis.Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry.The in vivo mutagenic frequency and specificity of O6-methylguanine in phi X174 replicative form DNA.
P2860
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P2860
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Chemical mutagenesis.
@en
type
label
Chemical mutagenesis.
@en
prefLabel
Chemical mutagenesis.
@en
P1476
Chemical mutagenesis.
@en
P2093
Kuśmierek JT
P304
P356
10.1146/ANNUREV.BI.51.070182.003255
P577
1982-01-01T00:00:00Z