P70 S6 kinase mediates tau phosphorylation and synthesis.
about
Phosphorylation of microtubule-associated protein tau by AMPK-related kinasesMulti-Target Directed Donepezil-Like Ligands for Alzheimer's DiseasemTOR-dependent signalling in Alzheimer's diseaseMammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseaseConfronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasisMechanisms of tau-induced neurodegeneration.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.Tau in Alzheimer disease and related tauopathies.Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.Structural principles of tau and the paired helical filaments of Alzheimer's disease.Dysfunction of the mTOR pathway is a risk factor for Alzheimer's disease.Cytosolic abnormally hyperphosphorylated tau but not paired helical filaments sequester normal MAPs and inhibit microtubule assemblyEarly glycogen synthase kinase-3β and protein phosphatase 2A independent tau dephosphorylation during global brain ischaemia and reperfusion following cardiac arrest and the role of the adenosine monophosphate kinase pathwayThe role of tau in Alzheimer's disease and related disorders.Targeting the mTOR signaling network for Alzheimer's disease therapy.Biometals and their therapeutic implications in Alzheimer's disease.Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer's Disease: Common Pathologies Potentiated by Altered Zinc Homeostasis.Activation of mTOR: a culprit of Alzheimer's disease?Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.Microtubule-Tau Interaction as a Therapeutic Target for Alzheimer's Disease.Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction.Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation.SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease.Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.Biometal Dyshomeostasis and Toxic Metal Accumulations in the Development of Alzheimer's Disease.Zinc Signal in Brain Diseases.Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope.PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3.mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice.Troglitazone, a peroxisome proliferator-activated receptor-gamma agonist, decreases tau phosphorylation in CHOtau4R cells.Interplay between glycogen synthase kinase-3β and tau in the cerebellum of Hsp27 transgenic mouseGlobal Approaches to Understanding Protein Kinase Functions
P2860
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P2860
P70 S6 kinase mediates tau phosphorylation and synthesis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
P70 S6 kinase mediates tau phosphorylation and synthesis.
@en
type
label
P70 S6 kinase mediates tau phosphorylation and synthesis.
@en
prefLabel
P70 S6 kinase mediates tau phosphorylation and synthesis.
@en
P2093
P2860
P50
P1433
P1476
P70 S6 kinase mediates tau phosphorylation and synthesis.
@en
P2093
Jan Norberg
Jin-Jing Pei
Takeshi Nishimura
Wen-Lin An
Xin-Wen Zhou
P2860
P304
P356
10.1016/J.FEBSLET.2005.11.059
P407
P577
2005-12-06T00:00:00Z