The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium.
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Clonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synoviumCell-cell interactions in synovitis: antigen presenting cells and T cell interaction in rheumatoid arthritis.Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritisHuman IgG Fc-binding phage antibodies constructed from synovial fluid CD38+ B cells of patients with rheumatoid arthritis show the imprints of an antigen-dependent process of somatic hypermutation and clonal selection.Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes.Roles of B cells in rheumatoid arthritisSynergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis.Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis.Identification of two new arthritis severity loci that regulate levels of autoantibodies, interleukin-1β, and joint damage in pristane- and collagen-induced arthritisWnt signalling in rheumatoid arthritis.Nurse-like cells from bone marrow and synovium of patients with rheumatoid arthritis promote survival and enhance function of human B cells.PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis.The roles of B cells and their interactions with fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis.Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression.Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.Synovial fluid mononuclear cells provide an environment for long-term survival of antibody-secreting cells and promote the spontaneous production of anti-citrullinated protein antibodies.Fibroblast-like synoviocytes support B-cell pseudoemperipolesis via a stromal cell-derived factor-1- and CD106 (VCAM-1)-dependent mechanism.Expression of B cell and immunoglobulin transcripts is a feature of inflammation in late allografts.PUMA gene delivery to synoviocytes reduces inflammation and degeneration of arthritic joints.Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab.Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts.TLR9 ligand induces the generation of CD20+ plasmablasts and plasma cells from CD27+ memory B-cells.Synovial biology and T cells in rheumatoid arthritis.Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF.Differential requirements for induction of total immunoglobulin and physiological rheumatoid factor production by human peripheral blood B cells.Rheumatoid factor isotype switch and somatic mutation variants within rheumatoid arthritis synovium.Activated human B cells induce inflammatory fibroblasts with cartilage-destructive properties and become functionally suppressed in return.
P2860
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P2860
The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
The ability of synoviocytes to ...... lation in rheumatoid synovium.
@en
type
label
The ability of synoviocytes to ...... lation in rheumatoid synovium.
@en
prefLabel
The ability of synoviocytes to ...... lation in rheumatoid synovium.
@en
P2093
P2860
P356
P1476
The ability of synoviocytes to ...... lation in rheumatoid synovium.
@en
P2093
P2860
P304
P356
10.1172/JCI117685
P407
P577
1995-02-01T00:00:00Z