Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.
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Mechanisms of Beta Cell Dysfunction Associated With Viral InfectionSensitization to self (virus) antigen by in situ expression of murine interferon-gamma.Achieving antigen-specific immune regulationIP-10 and type 1 diabetes: a question of time and location.Constitutive beta cell expression of IL-12 does not perturb self-tolerance but intensifies established autoimmune diabetes.Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus.Expression of adenoviral E3 transgenes in beta cells prevents autoimmune diabetes.Autoimmunity in picornavirus infections.Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice.Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma.SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3
P2860
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P2860
Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Focal expression of interleuki ...... an anti-self immune response.
@en
type
label
Focal expression of interleuki ...... an anti-self immune response.
@en
prefLabel
Focal expression of interleuki ...... an anti-self immune response.
@en
P2093
P2860
P356
P1476
Focal expression of interleuki ...... an anti-self immune response.
@en
P2093
J F Miller
M B Oldstone
M G von Herrath
P2860
P304
P356
10.1172/JCI117688
P407
P577
1995-02-01T00:00:00Z