Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells.
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Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia.Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysisExpression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes.Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional rolesRole of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases.2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors.Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.Chunghyuldan attenuates brain microglial inflammatory response.Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia.A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.The anti-inflammatory activity of a novel fused-cyclopentenone phosphonate and its potential in the local treatment of experimental colitis.Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant miceAdenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated processA new synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of the Akt/NF-κB pathway in BV2 microglial cells.Role of nonsynaptic communication in regulating the immune response.Anthocyanins downregulate lipopolysaccharide-induced inflammatory responses in BV2 microglial cells by suppressing the NF-κB and Akt/MAPKs signaling pathways.Investigational A₃ adenosine receptor targeting agents.Anti-inflammatory effect of ginsenoside Rg5 in lipopolysaccharide-stimulated BV2 microglial cells.G protein-coupled receptors as therapeutic targets for multiple sclerosis.The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-kappaB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis ratsG protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer.Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders.Emerging role of extracellular nucleotides and adenosine in multiple sclerosis.Adenosine receptor targeting in health and disease.The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators.(+)-Catechin Attenuates NF-κB Activation Through Regulation of Akt, MAPK, and AMPK Signaling Pathways in LPS-Induced BV-2 Microglial Cells.Regulation of microglial migration, phagocytosis, and neurite outgrowth by HO-1/CO signaling.Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury.Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells.A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.Activation of adenosine A3 receptor alleviates TNF-α-induced inflammation through inhibition of the NF-κB signaling pathway in human colonic epithelial cells.P1 receptors and cytokine secretion.Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats.Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts.Phlorofucofuroeckol A suppresses expression of inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines via inhibition of nuclear factor-κB, c-Jun NH2-terminal kinases, and Akt in microglial cells.MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson's disease.Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo.6,6'-Bieckol suppresses inflammatory responses by down-regulating nuclear factor-κB activation via Akt, JNK, and p38 MAPK in LPS-stimulated microglial cells.Ecto-5'-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice.
P2860
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P2860
Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Activation of adenosine A3 rec ...... n murine BV2 microglial cells.
@en
type
label
Activation of adenosine A3 rec ...... n murine BV2 microglial cells.
@en
prefLabel
Activation of adenosine A3 rec ...... n murine BV2 microglial cells.
@en
P2093
P1433
P1476
Activation of adenosine A3 rec ...... n murine BV2 microglial cells.
@en
P2093
Hyung Hwan Baik
Insug Kang
Ju Hie Lee
Jung Yeon Lee
Kyung-Sik Yoon
Sung Soo Kim
Wonchae Choe
Young Taek Oh
P356
10.1016/J.NEULET.2005.11.004
P407
P577
2005-12-01T00:00:00Z