Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.
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Distribution of mRNA for human epiregulin, a differentially expressed member of the epidermal growth factor familyDifferential expression of epidermal growth factor-related proteins in human colorectal tumorsA benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor geneAberrant regulation of transforming growth factor-alpha during the establishment of growth arrest and quiescence of growth factor independent cells.TGF-alpha expression as a potential biomarker of risk within the normal-appearing colorectal mucosa of patients with and without incident sporadic adenoma.Autocrine growth factors and solid tumor malignancy.Cell surface molecules and their prognostic values in assessing colorectal carcinomas.Jeremiah Metzger Lecture. Targeted cancer therapyRegulation of transforming growth factor alpha expression in a growth factor-independent cell lineApoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulinTransforming growth factor-alpha in vivo stimulates epithelial cell proliferation in digestive tissues of suckling ratsTransforming growth factors and receptor as potential modifiable pre-neoplastic biomarkers of risk for colorectal neoplasms.Roles for transforming growth factor-alpha in gastric physiology and pathophysiologyThe BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells.Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinomaInsulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factorGrowth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alphaModification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer modelEpidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.The level of epidermal growth factor receptors expression is correlated with the advancement of colorectal adenoma: validation of a surface biomarker.Cancer chemoprevention with green tea catechins by targeting receptor tyrosine kinases.The EGF/TGFalpha response element within the TGFalpha promoter consists of a multi-complex regulatory element.Role of EGF receptor ligands in TCDD-induced EGFR down-regulation and cellular proliferationGastrointestinal hormone mRNA expression in human colonic adenocarcinomas, hepatic metastases and cell lines.Expression of IL-10 receptors on epithelial cells from the murine small and large intestine.Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon.Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon.Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.Autocrine transforming growth factor alpha provides a growth advantage to malignant cells by facilitating re-entry into the cell cycle from suboptimal growth states.Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.
P2860
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P2860
Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Growth stimulation by coexpres ...... matous human colon epithelium.
@en
type
label
Growth stimulation by coexpres ...... matous human colon epithelium.
@en
prefLabel
Growth stimulation by coexpres ...... matous human colon epithelium.
@en
P2093
P2860
P356
P1476
Growth stimulation by coexpres ...... matous human colon epithelium.
@en
P2093
J K Willson
K Molkentin
S D Markowitz
T Stellato
P2860
P304
P356
10.1172/JCI114709
P407
P577
1990-07-01T00:00:00Z