Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms.
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Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesionDisruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsPost-translational modification-regulated leukocyte adhesion and migrationNMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tailsCharacterization of 14-3-3-ζ Interactions with Integrin TailsMelanoma upregulates ICAM-1 expression on endothelial cells through engagement of tumor CD44 with endothelial E-selectin and activation of a PKCα-p38-SP-1 pathway.A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells.The wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologuesStructural and mechanical functions of integrins.A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase.Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.An essential role for talin during alpha(M)beta(2)-mediated phagocytosisRegulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteinsActivation, coactivation, and costimulation of resting human natural killer cellsInterfering with leukocyte integrin activation--a novel concept in the development of anti-inflammatory drugs.Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling.Convergence of immunoreceptor and integrin signaling.Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions.Mechanisms of neutrophil transendothelial migrationRegulation of integrin activity and signallingLeukocyte integrins and their ligand interactions.EPAC proteins transduce diverse cellular actions of cAMP.New insights into the regulation and function of serine/threonine kinases in T lymphocytes.The ins and outs of leukocyte integrin signaling.Transdominant regulation of integrin function: mechanisms of crosstalk.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.Leucocyte recruitment in inflammation and novel endogenous negative regulators thereof.Neutrophil arrest by LFA-1 activationKindlin-3 in the immune system.Tuning Collective Cell Migration by Cell-Cell Junction Regulation.A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosisAn Alternative Phosphorylation Switch in Integrin β2 (CD18) Tail for Dok1 BindingThe β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo.Extravasation of leukocytes in comparison to tumor cells.Integrin CD11c/CD18 α-chain phosphorylation is functionally important.Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release.Recruitment of calcineurin to the TCR positively regulates T cell activation.
P2860
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P2860
Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Specific integrin alpha and be ...... t and -independent mechanisms.
@en
type
label
Specific integrin alpha and be ...... t and -independent mechanisms.
@en
prefLabel
Specific integrin alpha and be ...... t and -independent mechanisms.
@en
P2860
P356
P1476
Specific integrin alpha and be ...... t and -independent mechanisms.
@en
P2093
Susanna M Nurmi
Tiina J Hilden
P2860
P304
P356
10.1083/JCB.200504016
P407
P577
2005-11-01T00:00:00Z