Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12. - Wikidata - awgldk - TriplyDB

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

http://www.wikidata.org/entity/Q40350295

about

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production Siglecs and immune regulation EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual.Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells The immune inhibitory receptor LAIR-1 is highly expressed by plasmacytoid dendritic cells and acts complementary with NKp44 to control IFNα production.Plasmacytoid dendritic cells take up opsonized antigen leading to CD4+ and CD8+ T cell activation in vivo.DAP12 deficiency in liver allografts results in enhanced donor DC migration, augmented effector T cell responses and abrogation of transplant tolerance.In vivo conversion of BM plasmacytoid DC into CD11b+ conventional DC during virus infection.Deciphering the role of DC subsets in MCMV infection to better understand immune protection against viral infections Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cells Constitutive expression of TNF-related activation-induced cytokine (TRANCE)/receptor activating NF-κB ligand (RANK)-L by rat plasmacytoid dendritic cells.Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model.Siglec-mediated regulation of immune cell function in disease.Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells The kinetics of plasmacytoid dendritic cell accumulation in the pancreas of the NOD mouse during the early phases of insulitis.Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation.Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance Plasmacytoid dendritic cells contribute to systemic but not local antiviral responses to HSV infections.Plasmacytoid dendritic cell dichotomy: identification of IFN-α producing cells as a phenotypically and functionally distinct subset.The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.Plasmacytoid dendritic cells and the control of herpesvirus infections.The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases.Sex differences in murine susceptibility to systemic viral infections Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis.Plasmacytoid dendritic cells in atherosclerosis.Siglec-H protects from virus-triggered severe systemic autoimmunity.TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release.Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.Siglec1 suppresses antiviral innate immune response by inducing TBK1 degradation via the ubiquitin ligase TRIM27.

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P2860

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

http://www.wikidata.org/entity/Q40350295

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

@en

type

label

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

@en

prefLabel

Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

@en

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Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

@en

P2093

Amanda L Blasius

http://www.w3.org/2001/XMLSchema#string

Jorge Maldonado

http://www.w3.org/2001/XMLSchema#string

Toshiyuki Takai

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution

Recognition of sialylated meningococcal lipopolysaccharide by siglecs expressed on myeloid cells leads to enhanced bacterial uptake

Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation

Siglecs--the major subfamily of I-type lectins

Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors

Toll-like receptor control of the adaptive immune responses

The nature of the principal type 1 interferon-producing cells in human blood

Genetic and functional relationships between MHC and NK receptor genes.

Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44.

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2474-2476

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10.1182/BLOOD-2005-09-3746

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6

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16293595

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1895736

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