Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
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Amantadine and rimantadine for influenza A in children and the elderlyAmantadine and rimantadine for influenza A in children and the elderlyAmantadine and rimantadine for influenza A in children and the elderlyReview of the twelfth West Coast Retrovirus MeetingVpu Protein: The Viroporin Encoded by HIV-1Conformational changes induced by a single amino acid substitution in thetrans-membrane domain of Vpu: Implications for HIV-1 susceptibility to channel blocking drugsDrug sensitivity, drug-resistant mutations, and structures of three conductance domains of viral porins.Vpu matchmakers as a therapeutic strategy for HIV infection.Novel approaches to inhibiting HIV-1 replication.Mutations in the highly conserved SLQYLA motif of Vif in a simian-human immunodeficiency virus result in a less pathogenic virus and are associated with G-to-A mutations in the viral genome.Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release.Simian-Human immunodeficiency viruses expressing chimeric subtype B/C Vpu proteins demonstrate the importance of the amino terminal and transmembrane domains in the rate of CD4(+) T cell loss in macaques.The Vpu protein: new concepts in virus release and CD4 down-modulationThe lipophilic bullet hits the targets: medicinal chemistry of adamantane derivativesDeterminants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu proteinBST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-actionIdentification of Residues in the BST-2 TM Domain Important for Antagonism by HIV-1 Vpu Using a Gain-of-Function Approach.Bacteria-based analysis of HIV-1 Vpu channel activity.Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolateBST-2 mediated restriction of simian-human immunodeficiency virus.Comparison of the replication and persistence of simian-human immunodeficiency viruses expressing Vif proteins with mutation of the SLQYLA or HCCH domains in macaques.Identification of amino acids within the second alpha helical domain of the human immunodeficiency virus type 1 Vpu that are critical for preventing CD4 cell surface expression.
P2860
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P2860
Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Substitution of the transmembr ...... genic for pig-tailed macaques.
@en
type
label
Substitution of the transmembr ...... genic for pig-tailed macaques.
@en
prefLabel
Substitution of the transmembr ...... genic for pig-tailed macaques.
@en
P2093
P1433
P1476
Substitution of the transmembr ...... genic for pig-tailed macaques.
@en
P2093
Barbara Fegley
David M Pinson
David R Hout
Edward B Stephens
Ellyn R Mulcahy
Erik Pacyniak
Lisa M Gomez
M Sarah Hill
Melissa L Gomez
Michael F Powers
P304
P356
10.1016/J.VIROL.2005.08.022
P407
P577
2005-09-30T00:00:00Z