5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
about
Energy disruptors: rising stars in anticancer therapy?AMPK: a cellular metabolic and redox sensor. A minireviewLoss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretionsNanoceria: a rare-earth nanoparticle as a novel anti-angiogenic therapeutic agent in ovarian cancerIdentification of yeast and human 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) transportersAcadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell deathLactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoAActivation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivoAminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosisThymidylate synthase expression determines pemetrexed targets and resistance development in tumour cellsFanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolismSerine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.Bcl-2high mantle cell lymphoma cells are sensitized to acadesine with ABT-199.AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.AICAR inhibits proliferation and induced S-phase arrest, and promotes apoptosis in CaSki cells.Development of novel adenosine monophosphate-activated protein kinase activators.Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblastsmRNA-selective translation induced by FSH in primary Sertoli cellsAdiponectin represses colon cancer cell proliferation via AdipoR1- and -R2-mediated AMPK activationDissecting the role of AMP-activated protein kinase in human diseases.Preclinical therapeutic potential of a nitrosylating agent in the treatment of ovarian cancer.AMPK as a metabolic tumor suppressor: control of metabolism and cell growth.Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells.Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival.AMPK-Dependent Metabolic Regulation by PPAR Agonists.Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphateEffects of metformin on retinoblastoma growth in vitro and in vivo.AMPK as a therapeutic target in renal cell carcinoma.Ketogenic diets: from cancer to mitochondrial diseases and beyond.Plasticity in the purine-thiamine metabolic network of Salmonella.Prospects on strategies for therapeutically targeting oncogenic regulatory factors by small-molecule agentsNQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation."Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells".AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice modelMitochondrial effectors of cellular senescence: beyond the free radical theory of aging5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.
P2860
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P2860
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
5-Aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
type
label
5-Aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
prefLabel
5-Aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
P2093
P356
P1476
5-Aminoimidazole-4-carboxamide ...... AMP-activated protein kinase.
@en
P2093
Avtar K Singh
Inderjit Singh
Ramandeep Rattan
Shailendra Giri
P304
39582-39593
P356
10.1074/JBC.M507443200
P407
P577
2005-09-21T00:00:00Z