Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons.
about
Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient airMetabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometryApplication of biologically based computer modeling to simple or complex mixtures.Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouseComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterBenzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 daysLow-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cellsHuman aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbonsInterception of benzo[a]pyrene-7,8-dione by UDP glucuronosyltransferases (UGTs) in human lung cellsSynthesis of (13)C4-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyreneSynthesis of (13)C2-Benzo[a]pyrene and its 7,8-Dihydrodiol and 7,8-Dione Implicated as Carcinogenic MetabolitesQuantitation of benzo[a]pyrene metabolic profiles in human bronchoalveolar (H358) cells by stable isotope dilution liquid chromatography-atmospheric pressure chemical ionization mass spectrometryThe Role of Human Aldo-Keto Reductases in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH Catechols and PAH o-QuinonesPolycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouseDetoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTs) in human lung cellsMetabolism and distribution of benzo[a]pyrene-7,8-dione (B[a]P-7,8-dione) in human lung cells by liquid chromatography tandem mass spectrometry: detection of an adenine B[a]P-7,8-dione adductDetoxication of structurally diverse polycyclic aromatic hydrocarbon (PAH) o-quinones by human recombinant catechol-O-methyltransferase (COMT) via O-methylation of PAH catecholsEvidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cellsSensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient miceInfluence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesionCell cycle control, checkpoint mechanisms, and genotoxic stress.Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo[a,l]pyrene or its diol epoxides.Fluorescence line-narrowing detection in chromatography and electrophoresis.Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase.Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons.Formation and repair of tobacco carcinogen-derived bulky DNA adductsBioactivation of polycyclic aromatic hydrocarbon carcinogens within the vascular wall: implications for human atherogenesis.Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphismsAldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol.Aldo-keto reductases and formation of polycyclic aromatic hydrocarbon o-quinones.Benzo[a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate.Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.The role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skinMetabolically competent human skin models: activation and genotoxicity of benzo[a]pyrene.Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skinIdentification of stable benzo[a]pyrene-7,8-dione-DNA adducts in human lung cells.Carbocations from oxidized metabolites of benzo[a]anthracene: a computational study of their methylated and fluorinated derivatives and guanine adducts.Influence of structural and functional modifications of selected genotoxic carcinogens on metabolism and mutagenicity - a review.Comparative evaluation of different cell lysis and extraction methods for studying benzo(a)pyrene metabolism in HT-29 colon cancer cell cultures.
P2860
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P2860
Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Central role of radical cation ...... ycyclic aromatic hydrocarbons.
@en
type
label
Central role of radical cation ...... ycyclic aromatic hydrocarbons.
@en
prefLabel
Central role of radical cation ...... ycyclic aromatic hydrocarbons.
@en
P2860
P1433
P1476
Central role of radical cation ...... ycyclic aromatic hydrocarbons.
@en
P2093
E L Cavalieri
P2860
P304
P356
10.3109/00498259509061885
P407
P577
1995-07-01T00:00:00Z