Ezrin controls the macromolecular complexes formed between an adapter protein Na+/H+ exchanger regulatory factor and the cystic fibrosis transmembrane conductance regulator.
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Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targetsActivation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopyEPI64 regulates microvillar subdomains and structureAutoinhibitory Interactions between the PDZ2 and C-terminal Domains in the Scaffolding Protein NHERF1A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1Molecular conformation of the full-length tumor suppressor NF2/Merlin--a small-angle neutron scattering studyEzrin induces long-range interdomain allostery in the scaffolding protein NHERF1Phosphatidylinositol 4,5-bisphosphate clusters the cell adhesion molecule CD44 and assembles a specific CD44-Ezrin heterocomplex, as revealed by small angle neutron scatteringOpen conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scatteringNanoscale protein dynamics: a new frontier for neutron spin echo spectroscopyDifferential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.Engineering peptide inhibitors to overcome PDZ binding promiscuity.A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization.Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.IL-13 regulates cilia loss and foxj1 expression in human airway epithelium.CFTR Cl- channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish.Nanoscale protein domain motion and long-range allostery in signaling proteins- a view from neutron spin echo sprectroscopy.Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transportABC transporter architecture and regulatory roles of accessory domains.EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration.Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.The emerging role of PDZ adapter proteins for regulation of intestinal ion transport.PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system.The emerging contribution of sequence context to the specificity of protein interactions mediated by PDZ domains.Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions.Repairing the basic defect in cystic fibrosis - one approach is not enough.A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint.Visualizing the nanoscale: protein internal dynamics and neutron spin echo spectroscopy.Regulation of Transporters and Channels by Membrane-Trafficking Complexes in Epithelial Cells.Ezrin promotes functional expression and parathyroid hormone-mediated regulation of the sodium-phosphate cotransporter 2a in LLC-PK1 cells.NHE-RF1 protein rescues DeltaF508-CFTR function.Different conformational dynamics of PDZ1 and PDZ2 in full-length EBP50 analyzed by hydrogen/deuterium exchange mass spectrometry.The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling.Controllable Activation of Nanoscale Dynamics in a Disordered Protein Alters Binding Kinetics.
P2860
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P2860
Ezrin controls the macromolecular complexes formed between an adapter protein Na+/H+ exchanger regulatory factor and the cystic fibrosis transmembrane conductance regulator.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Ezrin controls the macromolecu ...... embrane conductance regulator.
@en
type
label
Ezrin controls the macromolecu ...... embrane conductance regulator.
@en
prefLabel
Ezrin controls the macromolecu ...... embrane conductance regulator.
@en
P2093
P2860
P921
P356
P1476
Ezrin controls the macromolecu ...... embrane conductance regulator.
@en
P2093
David J E Callaway
Deirdre Jana
Jianquan Li
Zhongping Dai
P2860
P304
37634-37643
P356
10.1074/JBC.M502305200
P407
P577
2005-08-28T00:00:00Z