Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.
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O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60Acromegaly pathogenesis and treatmentStructure of IL-22 bound to its high-affinity IL-22R1 chainJAK2 activation by growth hormone and other cytokinesMolecular mechanisms of prolactin and its receptorReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingA common model for cytokine receptor activation: combined scissor-like rotation and self-rotation of receptor dimer induced by class I cytokineCrystal Structure of an Affinity-matured Prolactin Complexed to Its Dimerized Receptor Reveals the Topology of Hormone Binding Site 2Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptorStructural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane ComplexStructure and Mechanism of Receptor Sharing by the IL-10R2 Common ChainStructural reorganization of the interleukin-7 signaling complexStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtiiLive cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneThe Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin.Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer CellsMinireview: mechanisms of growth hormone-mediated gene regulation.Let-7b Regulates Myoblast Proliferation by Inhibiting IGF2BP3 Expression in Dwarf and Normal Chicken.Insulin receptor activation with transmembrane domain ligands.Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3.Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.Human GH receptor-IGF-1 receptor interaction: implications for GH signaling.Dynamic analysis of GH receptor conformational changes by split luciferase complementation.Activation of transmembrane cell-surface receptors via a common mechanism? The "rotation model".Growth hormone-regulated mRNAs and miRNAs in chicken hepatocytesRole of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.A transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase DDR1.Intracellular signaling transduction pathways triggered by a well-known anti-GHR monoclonal antibody, Mab263, in vitro and in vivoMutations in FLS2 Ser-938 dissect signaling activation in FLS2-mediated Arabidopsis immunity.Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complexSingle-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cellsActivation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulationA Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase SignalingInhibitory GH receptor extracellular domain monoclonal antibodies: three-dimensional epitope mappingSignaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet β-cellsGDF-5 can act as a context-dependent BMP-2 antagonist.Relationship between initial treatment effect of recombinant human growth hormone and exon 3 polymorphism of growth hormone receptor in Chinese children with growth hormone deficiencyGrowth hormone-induced JAK2 signaling and GH receptor down-regulation: role of GH receptor intracellular domain tyrosine residues
P2860
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P2860
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Model for growth hormone recep ...... ation within a receptor dimer.
@en
type
label
Model for growth hormone recep ...... ation within a receptor dimer.
@en
prefLabel
Model for growth hormone recep ...... ation within a receptor dimer.
@en
P2093
P50
P921
P356
P1476
Model for growth hormone recep ...... ation within a receptor dimer.
@en
P2093
Julian J Adams
Karin A Eidne
Kathryn Palethorpe
Michael J Waters
Richard J Brown
Ruth M Seeber
Thea A Monks
P2888
P304
P356
10.1038/NSMB977
P577
2005-08-21T00:00:00Z