Acquired resistance to oestrogen deprivation: role for growth factor signalling kinases/oestrogen receptor cross-talk revealed in new MCF-7X model.
about
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivityDNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer.New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane.What do we know about the mechanisms of aromatase inhibitor resistance?Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expressionThe development, application and limitations of breast cancer cell lines to study tamoxifen and aromatase inhibitor resistanceEverolimus downregulates estrogen receptor and induces autophagy in aromatase inhibitor-resistant breast cancer cells.A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer.Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer.Lysine methylation of progesterone receptor at activation function 1 regulates both ligand-independent activity and ligand sensitivity of the receptor.Anticancer activities of artemisinin and its bioactive derivatives.Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro.Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth.Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways.Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines.Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance.
P2860
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P2860
Acquired resistance to oestrogen deprivation: role for growth factor signalling kinases/oestrogen receptor cross-talk revealed in new MCF-7X model.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Acquired resistance to oestrog ...... revealed in new MCF-7X model.
@en
type
label
Acquired resistance to oestrog ...... revealed in new MCF-7X model.
@en
prefLabel
Acquired resistance to oestrog ...... revealed in new MCF-7X model.
@en
P356
P1476
Acquired resistance to oestrog ...... k revealed in new MCF-7X model
@en
P2093
Cindy M Staka
Robert I Nicholson
P304
P356
10.1677/ERC.1.01006
P478
12 Suppl 1
P50
P577
2005-07-01T00:00:00Z