The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1.
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Key mechanisms governing resolution of lung inflammationInduction of eosinophil apoptosis by the cyclin-dependent kinase inhibitor AT7519 promotes the resolution of eosinophil-dominant allergic inflammationMolecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications.Kinase activity profiling of pneumococcal pneumoniaNeutrophil apoptosis: relevance to the innate immune response and inflammatory disease.Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - RoscovitineWogonin induces eosinophil apoptosis and attenuates allergic airway inflammationR-roscovitine reduces lung inflammation induced by lipoteichoic acid and Streptococcus pneumoniae.Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases.Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosisAsthma: beyond corticosteroid treatment.Mitochondria in the center of human eosinophil apoptosis and survivalEosinophils in the lung - modulating apoptosis and efferocytosis in airway inflammation.Switching off key signaling survival molecules to switch on the resolution of inflammation.Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition.Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammationDefining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia.Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance.Cyclin-dependent kinase 5 regulates degranulation in human eosinophils.
P2860
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P2860
The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The CDK inhibitor, R-roscoviti ...... s by down-regulation of Mcl-1.
@en
type
label
The CDK inhibitor, R-roscoviti ...... s by down-regulation of Mcl-1.
@en
prefLabel
The CDK inhibitor, R-roscoviti ...... s by down-regulation of Mcl-1.
@en
P2093
P2860
P1433
P1476
The CDK inhibitor, R-roscoviti ...... s by down-regulation of Mcl-1.
@en
P2093
Adriano G Rossi
Ana L Alessandri
Andrew E Leitch
Christopher Haslett
Colette Meyer
Hugh J Brady
Ian Dransfield
John M Hallett
Mauro M Teixeira
Morag C Martin
P2860
P304
P356
10.1016/J.FEBSLET.2009.07.017
P407
P577
2009-07-18T00:00:00Z