Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine.
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Regulation of glutathione synthesisGlutathione synthesisGlutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor.The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species.A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae.The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae.The yeast ubiquitin ligase SCFMet30 regulates heavy metal responsePhysiological and pathological aspects of GSH metabolismDifferent Polar Metabolites and Protein Profiles between High- and Low-Quality Japanese Ginjo SakeA genetic investigation of the essential role of glutathione: mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast.Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeastGene expression in secondary metabolism and metabolic switching phase of Phanerochaete chrysosporium.YCF1-mediated cadmium resistance in yeast is dependent on copper metabolism and antioxidant enzymes.γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo.A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis.Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development.Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicansRegulation of redox homeostasis in the yeast Saccharomyces cerevisiae.The response to heat shock and oxidative stress in Saccharomyces cerevisiaeγ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor.Dissecting the role of glutathione biosynthesis in Plasmodium falciparum.Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants.Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.Glutathione and γ-glutamylcysteine in the antioxidant and survival functions of mitochondria.Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors.Role and Regulation of Glutathione Metabolism in Plasmodium falciparum.Differential protein S-thiolation of glyceraldehyde-3-phosphate dehydrogenase isoenzymes influences sensitivity to oxidative stress.Disruption of redox homeostasis and induction of apoptosis by suppression of glutathione synthetase expression in a mammalian cell line.Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: involvement of a respiration-related process for maximal sensitivity and adaptive response.Glutathione plays a fundamental role in growth and symbiotic capacity of Sinorhizobium meliloti.Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae.Glutathione degradation is a key determinant of glutathione homeostasis.Absolute transcript levels of thioredoxin- and glutathione-dependent redox systems in Saccharomyces cerevisiae: response to stress and modulation with growth.The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae.Glutathione participates in the regulation of mitophagy in yeastRole of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae.Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis.Essential role of glutathione in acclimation to environmental and redox perturbations in the cyanobacterium Synechocystis sp. PCC 6803.Monitoring disulfide bond formation in the eukaryotic cytosol.Engineering glutathione biosynthesis of Saccharomyces cerevisiae increases robustness to inhibitors in pretreated lignocellulosic materials.
P2860
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P2860
Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Glutathione synthetase is disp ...... eptide gamma-glutamylcysteine.
@en
type
label
Glutathione synthetase is disp ...... eptide gamma-glutamylcysteine.
@en
prefLabel
Glutathione synthetase is disp ...... eptide gamma-glutamylcysteine.
@en
P2860
P356
P1476
Glutathione synthetase is disp ...... eptide gamma-glutamylcysteine.
@en
P2093
P2860
P304
P356
10.1091/MBC.8.9.1699
P577
1997-09-01T00:00:00Z