Nuclear autoantigen translocation and autoantibody opsonization lead to increased dendritic cell phagocytosis and presentation of nuclear antigens: a novel pathogenic pathway for autoimmunity?
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Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigensHow apoptotic cells aid in the removal of their own cold dead bodiesThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityGeneration of populations of antigen-specific cytotoxic T cells using DCs transfected with DNA construct encoding HER2/neu tumor antigen epitopes.Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosisInefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells.Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus.Human parvovirus B19 induced apoptotic bodies contain altered self-antigens that are phagocytosed by antigen presenting cells.An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells.Cuts can kill: the roles of apoptotic nucleases in cell death and animal development.Apoptotic cell death and lupus.Dendritic cells and the immunopathogenesis of systemic lupus erythematosus.Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responsesPathophysiology of cutaneous lupus erythematosus.Apoptosis in the pathogenesis of systemic lupus erythematosus.The consequences of apoptosis in autoimmunity.Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus DevelopmentCellular and nuclear degradation during apoptosis.Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation.9G4+ autoantibodies are an important source of apoptotic cell reactivity associated with high levels of disease activity in systemic lupus erythematosus.The role of dendritic cells in the pathogenesis of systemic lupus erythematosus.TLR7 and TLR9 in SLE: when sensing self goes wrong.The immunophysiology and apoptosis of biliary epithelial cells: primary biliary cirrhosis and primary sclerosing cholangitis.From the nucleus to the plasma membrane: translocation of the nuclear proteins histone H3 and lamin B1 in apoptotic microglia.An experimental protocol for the fractionation and 2DE separation of HeLa and A-253 cell lysates suitable for the identification of the individual antigenic proteome in Sjögren's syndrome.Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17.The regulation of autoreactive B cells during innate immune responses.Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus.
P2860
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P2860
Nuclear autoantigen translocation and autoantibody opsonization lead to increased dendritic cell phagocytosis and presentation of nuclear antigens: a novel pathogenic pathway for autoimmunity?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Nuclear autoantigen translocat ...... enic pathway for autoimmunity?
@en
type
label
Nuclear autoantigen translocat ...... enic pathway for autoimmunity?
@en
prefLabel
Nuclear autoantigen translocat ...... enic pathway for autoimmunity?
@en
P2093
P1476
Nuclear autoantigen translocat ...... enic pathway for autoimmunity?
@en
P2093
Lenese McPhie
Lorenza Frisoni
Lucrezia Colonna
Marc Monestier
Roberto Caricchio
Stefania Gallucci
Uma Sriram
P304
P356
10.4049/JIMMUNOL.175.4.2692
P407
P577
2005-08-01T00:00:00Z