Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells.
about
Progress and prospects for engineered T cell therapiesRecent advance in antigen-specific immunotherapy for acute myeloid leukemiaT cell receptor-like recognition of tumor in vivo by synthetic antibody fragmentStructural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restrictionT-cell receptor gene therapy--ready to go viral?Graft-versus-leukemia effect of HLA-haploidentical central-memory T-cells expanded with leukemic APCs and modified with a suicide geneSelection of human antibody fragments directed against tumor T-cell epitopes for adoptive T-cell therapy.Development of a Wilms' tumor antigen-specific T-cell receptor for clinical trials: engineered patient's T cells can eliminate autologous leukemia blasts in NOD/SCID miceTransduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity.Mixed T cell receptor dimers harbor potentially harmful neoreactivity.Treatment of 4T1 metastatic breast cancer with combined hypofractionated irradiation and autologous T-cell infusion.Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccinationImmunotherapy of human cancers using gene modified T lymphocytes.Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigenAdoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation.Generation of diffuse large B cell lymphoma-associated antigen-specific Vα6/Vβ13+T cells by TCR gene transfer.Clinical application of genetically modified T cells in cancer therapy.Detection and preliminary characterization of CD8+T lymphocytes specific for Wilms' tumor antigen in patients with non-Hodgkin lymphoma.Loss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo.Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer.Genetically retargeting CD8+ lymphocyte subsets for cancer immunotherapy.Human cancer growth and therapy in immunodeficient mouse models.NCI First International Workshop on The Biology, Prevention and Treatment of Relapse after Allogeneic Hematopoietic Cell Transplantation: report from the committee on prevention of relapse following allogeneic cell transplantation for hematologic maAdoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.Improving TCR Gene Therapy for Treatment of Haematological Malignancies.Facilitating matched pairing and expression of TCR chains introduced into human T cells.Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1(+) leukemias.Genetic modification of human T lymphocytes for the treatment of hematologic malignancies.Exploiting beneficial alloreactive T cells.Cellular therapies in acute lymphoblastic leukemiaNY-ESO-1 immunotherapy for multiple myeloma.Can immunotherapy specifically target acute myeloid leukemic stem cells?Chimeric Antigen Receptor T-Cell Therapy for the Community OncologistGenetic modification of T cells for immunotherapy.T-cell receptor gene therapy for cancer: the progress to date and future objectives.A High-avidity WT1-reactive T-Cell Receptor Mediates Recognition of Peptide and Processed Antigen but not Naturally Occurring WT1-positive Tumor Cells.TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.Full-intensity and reduced-intensity allogeneic stem cell transplantation in AML.Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8(+) T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cellsIncreasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.
P2860
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P2860
Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Elimination of human leukemia ...... gene-transduced human T cells.
@en
type
label
Elimination of human leukemia ...... gene-transduced human T cells.
@en
prefLabel
Elimination of human leukemia ...... gene-transduced human T cells.
@en
P2093
P1433
P1476
Elimination of human leukemia ...... gene-transduced human T cells.
@en
P2093
Adrian Thrasher
Boris Engels
Daniel Hart
Emma Morris
Hans Stauss
Jane Apperley
Liquan Gao
Roopinder Gillmore
Shao-An Xue
Wolfgang Uckert
P304
P356
10.1182/BLOOD-2005-01-0146
P407
P50
P577
2005-07-14T00:00:00Z