Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.
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Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosinesThe Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active SiteYeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycolLethal mutagenesis of HIV with mutagenic nucleoside analogsFormation and persistence of 8-oxoguanine in rat lung cells as an important determinant for tumor formation following particle exposureUnexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variabilityThe genes encoding endonuclease VIII and endonuclease III in Escherichia coli are transcribed as the terminal genes in operons.A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G-->T transversions.Multiprobe RNase protection assay analysis of mRNA levels for the Escherichia coli oxidative DNA glycosylase genes under conditions of oxidative stress.2'-Deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA.A genotyping strategy based on incorporation and cleavage of chemically modified nucleotides.Recent advances in the structural mechanisms of DNA glycosylasesRepair of products of oxidative DNA base damage in human cellsArtifacts associated with the measurement of oxidized DNA bases.Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIIIDehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC)5-Hydroxypyrimidine deoxynucleoside triphosphates are more efficiently incorporated into DNA by exonuclease-free Klenow fragment than 8-oxopurine deoxynucleoside triphosphatesOxidative DNA damage: biological significance and methods of analysis.Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summarySynthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidineEscherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutantsThermodynamic signature of DNA damage: characterization of DNA with a 5-hydroxy-2'-deoxycytidine·2'-deoxyguanosine base pair.Oxidized, deaminated cytosines are a source of C --> T transitions in vivoSynthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.Mitochondria, oxidative DNA damage, and agingDrug-induced oxidative stress and toxicity.Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine.Detection of p53 mutations in precancerous gastric tissue.Excess processing of oxidative damaged bases causes hypersensitivity to oxidative stress and low dose rate irradiation.8-Hydroxyadenine (7,8-dihydro-8-oxoadenine) induces misincorporation in in vitro DNA synthesis and mutations in NIH 3T3 cells.DNA damages processed by base excision repair: biological consequences.Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancerPhysical and functional interactions between Escherichia coli MutY and endonuclease VIIIFormation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repairThree nth homologs are all required for efficient repair of spontaneous DNA damage in Deinococcus radiodurans.Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase.Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII.Genotoxicity of 5-aminolevulinic and 4,5-dioxovaleric acids in the salmonella/microsuspension mutagenicity assay and SOS chromotest.The evaluation of 5-amino- and 5-hydroxyuracil derivatives as potential quadruplex-forming agents.Glutathione and ascorbate are negatively correlated with oxidative DNA damage in human lymphocytes.
P2860
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P2860
Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Major oxidative products of cy ...... dependent mispairing in vitro.
@en
type
label
Major oxidative products of cy ...... dependent mispairing in vitro.
@en
prefLabel
Major oxidative products of cy ...... dependent mispairing in vitro.
@en
P2860
P356
P1476
Major oxidative products of cy ...... -dependent mispairing in vitro
@en
P2093
P2860
P356
10.1093/NAR/22.1.72
P577
1994-01-01T00:00:00Z