Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells. - Wikidata - awgldk - TriplyDB

Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells.

Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells.

http://www.wikidata.org/entity/Q40399606

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Apigenin sensitizes prostate cancer cells to Apo2L/TRAIL by targeting adenine nucleotide translocase-2 Luteolin, a flavonoid with potential for cancer prevention and therapy Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinase signaling pathway.Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53 Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.Inhibitory effects and mechanisms of luteolin on proliferation and migration of vascular smooth muscle cells.Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin Anti-carcinogenic effects of the flavonoid luteolin.Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors.Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1.Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells.Traditional Chinese Herbal Medicine Penthorum chinense Pursh: A Phytochemical and Pharmacological Review.Elmenols C-H, new angucycline derivatives isolated from a culture of Streptomyces sp. IFM 11490.Enhanced anticancer activity in vitro and in vivo of luteolin incorporated into long-circulating micelles based on DSPE-PEG2000 and TPGS.New phenazine analogues from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activities.Sulfotanone, a new alkyl sulfonic acid derivative from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activity.The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages.Chrysin, apigenin and acacetin inhibit tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) on activated RAW264.7 macrophages.Chromomycins A2 and A3 from marine actinomycetes with TRAIL resistance-overcoming and Wnt signal inhibitory activities 2'-hydroxyflavanone induces apoptosis of human osteosarcoma 143 B cells by activating the extrinsic TRAIL- and intrinsic mitochondria-mediated pathways.Luteolin induces apoptosis by activating Fas signaling pathway at the receptor level in laryngeal squamous cell line Hep-2 cells.Yoropyrazone, a new naphthopyridazone alkaloid isolated from Streptomyces sp. IFM 11307 and evaluation of its TRAIL resistance-overcoming activity.New pyranonaphthoquinones and a phenazine alkaloid isolated from Streptomyces sp. IFM 11307 with TRAIL resistance-overcoming activity.Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: involvement of cell line-specific apoptotic mechanisms.Flavones inhibit the proliferation of human tumor cancer cell lines by inducing apoptosis.Isolation and structure elucidation of izuminosides A-C: a rare phenazine glycosides from Streptomyces sp. IFM 11260.Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells.Caspase activation and extracellular signal-regulated kinase/Akt inhibition were involved in luteolin-induced apoptosis in Lewis lung carcinoma cells.Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin."Combination-oriented molecular-targeting prevention" of cancer: a model involving the combination of TRAIL and a DR5 inducer.Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.Myricetin blocks lipoteichoic acid-induced COX-2 expression in human gingival fibroblasts.Dietary flavonoids sensitize HeLa cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).Sharkquinone, a new ana-quinonoid tetracene derivative from marine-derived Streptomyces sp. EGY1 with TRAIL resistance-overcoming activity.Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways.Modulation of G2/M cell cycle arrest and apoptosis by luteolin in human colon cancer cells and xenografts.Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.Quercus Suber L. Cork Extracts Induce Apoptosis in Human Myeloid Leukaemia HL-60 Cells.

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Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells.

http://www.wikidata.org/entity/Q40399606

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Hiroshi Matsui

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Hoyoku Nishino

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Mano Horinaka

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Miki Wakada

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Ryoko Nakanishi

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Susumu Nakata

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Takumi Shiraishi

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Tatsushi Yoshida

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Toshiyuki Sakai

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P2860

Caspase-10 is an initiator caspase in death receptor signaling

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

Safety and antitumor activity of recombinant soluble Apo2 ligand.

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells.

Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants.

How melanoma cells evade trail-induced apoptosis.

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

Death receptors as targets of cancer therapeutics.

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16007131

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