The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA
about
Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activityThe mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKRThe human La (SS-B) autoantigen interacts with DDX15/hPrp43, a putative DEAH-box RNA helicase.The La antigen binds 5' noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translationRecognition of nascent RNA by the human La antigen: conserved and divergent features of structure and functionAnalysis of the molecular composition of Ro ribonucleoprotein complexesDouble-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18Efficient synthesis, termination and release of RNA polymerase III transcripts in Xenopus extracts depleted of La protein.Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme.General RNA binding proteins render translation cap dependent.Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response.TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress.Selective translation of the measles virus nucleocapsid mRNA by la protein.Intracellular redistribution of truncated La protein produced by poliovirus 3Cpro-mediated cleavage.Transcription efficiency of human polymerase III genes in vitro does not depend on the RNP-forming autoantigen La.Inhibition of internal ribosomal entry site-directed translation of HCV by recombinant IFN-alpha correlates with a reduced La protein.A diminished activation capacity of the interferon-inducible protein kinase PKR in human T lymphocytes.The human autoantigen La/SS-B accelerates herpes simplex virus type 1 replication in transfected mouse 3T3 cells.Xlrbpa, a double-stranded RNA-binding protein associated with ribosomes and heterogeneous nuclear RNPs
P2860
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P2860
The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The La antigen inhibits the ac ...... unwinding double-stranded RNA
@en
type
label
The La antigen inhibits the ac ...... unwinding double-stranded RNA
@en
prefLabel
The La antigen inhibits the ac ...... unwinding double-stranded RNA
@en
P2093
P2860
P356
P1476
The La antigen inhibits the ac ...... unwinding double-stranded RNA
@en
P2093
G J Pruijn
I W Jeffrey
M J Clemens
W J van Venrooij
P2860
P304
P356
10.1093/NAR/22.13.2512
P577
1994-07-01T00:00:00Z