Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter. - Wikidata - awgldk - TriplyDB

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter.

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter.

http://www.wikidata.org/entity/Q40412449

about

Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation Inhibition of NF-AT-dependent transcription by NF-kappa B: implications for differential gene expression in T helper cell subsets The gene for the human architectural transcription factor HMGI-C consists of five exons each coding for a distinct functional element Expression of NFAT-family proteins in normal human T cells Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression Functional interaction between the DNA binding subunit trimerization domain of NF-Y and the high mobility group protein HMG-I(Y)Calcineurin-dependent nuclear translocation of a murine transcription factor NFATx: molecular cloning and functional characterization Mina, an Il4 repressor, controls T helper type 2 bias HMGA1 and HMGA2 protein expression in mouse spermatogenesis Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells Mining microarray data to identify transcription factors expressed in naïve resting but not activated T lymphocytes.HMGA1a recognition candidate DNA sequences in humans.The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development.Transcriptional regulation of BK virus by nuclear factor of activated T cells.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy.Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells Requirement for transcription factor NFAT in interleukin-2 expression RETRACTED: Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation.Regulation of interleukin 4 gene transcription: alterations in atopic disease?Molecular genetics of benign tumors.Regulation of IL4 gene expression by T cells and therapeutic perspectives.HMGA proteins: flexibility finds a nuclear niche?Warner-Lambert/Parke-Davis Award lecture. Many tumors and many genes: genetics of uterine leiomyomata HMGI(Y) expression in human uterine leiomyomata. Involvement of another high-mobility group architectural factor in a benign neoplasm A retrospective study of high mobility group protein I(Y) as progression marker for prostate cancer determined by in situ hybridization.Cytokine transcriptional events during helper T cell subset differentiation.Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells Nuclear factor of activated T cells balances angiogenesis activation and inhibition.Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex.HMG I(Y) interferes with the DNA binding of NF-AT factors and the induction of the interleukin 4 promoter in T cells.Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.Multivalent DNA-binding properties of the HMG-1 proteins.Transcriptional control of T-cell development.

P2860

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P2860

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter.

http://www.wikidata.org/entity/Q40412449

description

1993 nî lūn-bûn

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1993年の論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

@zh-tw

1993年论文

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1993年论文

@zh

1993年论文

@zh-cn

name

Multiple closely-linked NFAT/o ...... of the interleukin-4 promoter.

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type

label

Multiple closely-linked NFAT/o ...... of the interleukin-4 promoter.

@en

prefLabel

Multiple closely-linked NFAT/o ...... of the interleukin-4 promoter.

@en

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Nucleic Acids Research

P1476

Multiple closely-linked NFAT/o ...... of the interleukin-4 promoter.

@en

P2093

Chuvpilo S

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Gerwig R

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Grummt F

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Heinfling A

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Reeves R

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Schomberg C

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Serfling E

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P2860

Identification of a zinc finger protein that inhibits IL-2 gene expression

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

A versatile in vivo and in vitro eukaryotic expression vector for protein engineering

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

A novel, inducible and T cell-specific enhancer located at the 3' end of the T cell receptor alpha locus.

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5694-5704

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10.1093/NAR/21.24.5694

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24

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21

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1993-12-01T00:00:00Z

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14915511

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8284217

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310537

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