Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas.
about
Role of siglecs and related glycan-binding proteins in immune responses and immunoregulationUnmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.Synthesis and labeling of α-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells.Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches.Sialic acids in biological and therapeutic processes: opportunities and challenges.New Human CD22/Siglec-2 Ligands with a Triazole Glycoside.Molecular basis of human CD22 function and therapeutic targeting.Oxidative Deamination of N-Acetyl Neuraminic Acid: Substituent Effects and Mechanism.The isothiocyanato moiety: an ideal protecting group for the stereoselective synthesis of sialic acid glycosides and subsequent diversification.CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells.Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.Non-Covalent Assembly Method that Simultaneously Endows a Liposome Surface with Targeting Ligands, Protective PEG Chains, and Deep-Red Fluorescence Reporter Groups.Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling.Screening of Neu5Acα(2-6)gal isomer preferences of siglecs with a sialic acid microarray.Detection of mSiglec-E, in solution and expressed on the surface of Chinese hamster ovary cells, using sialic acid functionalised gold nanoparticles.Cell-based glycan arrays for probing glycan-glycan binding protein interactions.CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.
P2860
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P2860
Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Disubstituted Sialic Acid Liga ...... ukaemias and B Cell Lymphomas.
@en
type
label
Disubstituted Sialic Acid Liga ...... ukaemias and B Cell Lymphomas.
@en
prefLabel
Disubstituted Sialic Acid Liga ...... ukaemias and B Cell Lymphomas.
@en
P2093
P2860
P356
P1433
P1476
Disubstituted Sialic Acid Liga ...... ukaemias and B Cell Lymphomas.
@en
P2093
Britni M Arlian
Cory D Rillahan
Erik Schwartz
James C Paulson
Janani Rangarajan
Ryan McBride
P2860
P304
P356
10.1039/C4SC00451E
P577
2014-06-01T00:00:00Z