The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans.
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Calcineurin-Crz1 signaling in lower eukaryotesGenetic architecture of Hsp90-dependent drug resistance.Regulatory roles of phosphorylation in model and pathogenic fungiHsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurinHsp90 orchestrates stress response signaling governing fungal drug resistanceCalcineurin signaling and membrane lipid homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicansCalcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniaeFunctional characterization of an Aspergillus fumigatus calcium transporter (PmcA) that is essential for fungal infectionHsp21 potentiates antifungal drug tolerance in Candida albicansA phenotypic profile of the Candida albicans regulatory network.Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.A 5' UTR-mediated translational efficiency mechanism inhibits the Candida albicans morphological transition.Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.Lack of trehalose accelerates H2O2-induced Candida albicans apoptosis through regulating Ca2+ signaling pathway and caspase activity.Regulatory circuitry governing fungal development, drug resistance, and disease.Disruption of the transcriptional regulator Cas5 results in enhanced killing of Candida albicans by FluconazoleDirect effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus speciesIn Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone against Aspergillus fumigatus.Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance.The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanismsAn update on antifungal targets and mechanisms of resistance in Candida albicans.Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformansCalcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus.The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistanceEfflux-mediated antifungal drug resistance.Signaling cascades as drug targets in model and pathogenic fungi.The Hsp90 Co-chaperones Sti1, Aha1, and P23 Regulate Adaptive Responses to Antifungal Azoles.Medically important fungi respond to azole drugs: an update.Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy.Calcineurin modulates growth, stress tolerance, and virulence in Metarhizium acridum and its regulatory network.The PKC, HOG and Ca2+ signalling pathways co-ordinately regulate chitin synthesis in Candida albicans.Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.Regulation of salt tolerance by Torulaspora delbrueckii calcineurin target Crz1p.Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.Overexpression of the calcineurin target CRZ1 provides freeze tolerance and enhances the fermentative capacity of baker's yeast.Calcineurin is required for Candida albicans to survive calcium stress in serum.Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms.Genetic bypass of Aspergillus nidulans crzA function in calcium homeostasis.
P2860
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P2860
The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
The calcineurin target, Crz1, ...... virulence of Candida albicans.
@en
type
label
The calcineurin target, Crz1, ...... virulence of Candida albicans.
@en
prefLabel
The calcineurin target, Crz1, ...... virulence of Candida albicans.
@en
P2860
P1476
The calcineurin target, Crz1, ...... virulence of Candida albicans.
@en
P2093
Chiatogu Onyewu
Floyd L Wormley
P2860
P304
P356
10.1128/IAI.72.12.7330-7333.2004
P407
P577
2004-12-01T00:00:00Z