CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro.
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Enhancing Cancer Immunotherapy Via Activation of Innate ImmunityCD40 immunotherapy for pancreatic cancerMacrophage: SHIP of ImmunityDevelopment of optical probes for in vivo imaging of polarized macrophages during foreign body reactions.Tumor-associated macrophages (TAMs) form an interconnected cellular supportive network in anaplastic thyroid carcinoma.Role of endogenous IFN-gamma in macrophage programming induced by IL-12 and IL-18.Macrophages in multiple myeloma: emerging concepts and therapeutic implications.Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells.Enhanced T-cell-independent antitumor effect of cyclophosphamide combined with anti-CD40 mAb and CpG in mice.Anti-tumor and immunomodulatory activity of resveratrol in vitro and its potential for combining with cancer immunotherapy.Synergy of anti-CD40, CpG and MPL in activation of mouse macrophagesTumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple MyelomaCancer immunoediting by the innate immune system in the absence of adaptive immunity.Intratumoral delivery of low doses of anti-CD40 mAb combined with monophosphoryl lipid a induces local and systemic antitumor effects in immunocompetent and T cell-deficient mice.Tumor-associated myeloid cells can be activated in vitro and in vivo to mediate antitumor effectsEnhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpGIFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic CarcinomaIntratumoral immunocytokine treatment results in enhanced antitumor effects.Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation.Virus-based immunotherapy of cancer: what do we know and where are we going?Murine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy.Twelve immunotherapy drugs that could cure cancers.Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemiaNaive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules.Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages.Antitumor effects of anti-CD40/CpG immunotherapy combined with gemcitabine or 5-fluorouracil chemotherapy in the B16 melanoma model.The use of agonistic anti-CD40 therapy in treatments for cancer.T-cell-independent antitumor effects of CD40 ligation.Anti-tumour strategies aiming to target tumour-associated macrophages.Intratumoral injection of Ad-ISF35 (Chimeric CD154) breaks tolerance and induces lymphoma tumor regression.Enhanced therapeutic anti-tumor immunity induced by co-administration of 5-fluorouracil and adenovirus expressing CD40 ligand.Macrophage Polarization: Anti-Cancer Strategies to Target Tumor-Associated Macrophage in Breast Cancer.Nanomedicine Strategies to Target Tumor-Associated Macrophages.CD40 pathway activation reveals dual function for macrophages in human endometrial cancer cell survival and invasion.Measurement of tumor cytolysis by macrophages.Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors.MicroRNA: Dynamic Regulators of Macrophage Polarization and Plasticity.Defective antitumor responses in CX3CR1-deficient mice.
P2860
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P2860
CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
CD40 ligation activates murine ...... mor cell destruction in vitro.
@en
type
label
CD40 ligation activates murine ...... mor cell destruction in vitro.
@en
prefLabel
CD40 ligation activates murine ...... mor cell destruction in vitro.
@en
P2093
P1476
CD40 ligation activates murine ...... mor cell destruction in vitro.
@en
P2093
Alexander L Rakhmilevich
Donna M Paulnock
Gideon Berke
Hillary Lum
Ilia N Buhtoiarov
Paul M Sondel
P304
P356
10.4049/JIMMUNOL.174.10.6013
P407
P577
2005-05-01T00:00:00Z