Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.
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Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyraseGenomic transcriptional response to loss of chromosomal supercoiling in Escherichia coliRotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxationHoloenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VIA naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogsMechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs: II. THE SHAPE OF THE GyrA SUBUNIT C-TERMINAL DOMAIN (CTD) IS NOT A SOLE DETERMINANT FOR CONTROLLING SUPERCOILING EFFICIENCYStructural basis for the MukB-topoisomerase IV interaction and its functional implicationsin vivoMycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxesTopoisomerase IV, alone, unknots DNA in E. coliTopoisomerase II can unlink replicating DNA by precatenane removalChirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases.Mechanisms of chiral discrimination by topoisomerase IVForce and twist dependence of RepC nicking activity on torsionally-constrained DNA molecules.Determination of thermodynamics and kinetics of RNA reactions by force.The dynamic interplay between DNA topoisomerases and DNA topology.Helical chirality: a link between local interactions and global topology in DNASimulation of DNA catenanes.DNA supercoiling and its role in DNA decatenation and unknotting.DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsKThe C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold.Single-molecule measurements of DNA topology and topoisomerases.Differential stability of DNA crossovers in solution mediated by divalent cations.A gyrase mutant with low activity disrupts supercoiling at the replication terminusThe mechanism of type IA topoisomerases.A topological view of the repliconTopological challenges to DNA replication: conformations at the forkTopoisomerase IV bends and overtwists DNA upon binding.DNA axial rotation and the merge of oppositely supercoiled DNA domains in Escherichia coli: effects of DNA bendsHow topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation.Phylogenomics of DNA topoisomerases: their origin and putative roles in the emergence of modern organisms.Distribution of gyrase and topoisomerase IV on bacterial nucleoid: implications for nucleoid organization.Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.All tangled up: how cells direct, manage and exploit topoisomerase function.Magnetic tweezers: a sensitive tool to study DNA and chromatin at the single-molecule level.Electrostatic braiding and homologous pairing of DNA double helices.Unlinking of supercoiled DNA catenanes by type IIA topoisomerases.Linear ordering and dynamic segregation of the bacterial chromosomeLocal sensing of global DNA topology: from crossover geometry to type II topoisomerase processivityGeminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cellsDirect Evidence for the Formation of Precatenanes during DNA Replication
P2860
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P2860
Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Preferential relaxation of pos ...... ule and ensemble measurements.
@en
type
label
Preferential relaxation of pos ...... ule and ensemble measurements.
@en
prefLabel
Preferential relaxation of pos ...... ule and ensemble measurements.
@en
P2093
P2860
P356
P1433
P1476
Preferential relaxation of pos ...... cule and ensemble measurements
@en
P2093
D Bensimon
N J Crisona
N R Cozzarelli
P2860
P304
P356
10.1101/GAD.838900
P577
2000-11-01T00:00:00Z