Nuclear organization of DNA replication in primary mammalian cells.
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Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcriptionRBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrestAccumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndromeFunctional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrestReplication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cellsAltered protein dynamics of disease-associated lamin A mutantsThe retinoblastoma family: twins or distant cousins?Differential role of RB in response to UV and IR damage.Defining multiple, distinct, and shared spatiotemporal patterns of DNA replication and endoreduplication from 3D image analysis of developing maize (Zea mays L.) root tip nuclei.4D Visualization of replication foci in mammalian cells corresponding to individual repliconsLamin A/C and emerin are critical for skeletal muscle satellite cell differentiationp53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.Cdc45 limits replicon usage from a low density of preRCs in mammalian cellsClick chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data fileCell size checkpoint control by the retinoblastoma tumor suppressor pathwayEvidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2.The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent mannerGenomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication.Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformationCell-extrinsic defective lymphocyte development in Lmna(-/-) mice.Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction.Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cellsCentromere-localized breaks indicate the generation of DNA damage by the mitotic spindle.p107 in the public eye: an Rb understudy and more.Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territoriesDrosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication.DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndromeFunctions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery-Dreifuss muscular dystrophy.A moving DNA replication factory in Caulobacter crescentusDrosophila cyclin E interacts with components of the Brahma complexNuclear lamins.The lamin protein family.DNA methylation, chromatin inheritance, and cancer.Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situLamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.DNA replication and nuclear architecture.Nucleoplasmic lamins and their interaction partners, LAP2alpha, Rb, and BAF, in transcriptional regulation.
P2860
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P2860
Nuclear organization of DNA replication in primary mammalian cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Nuclear organization of DNA replication in primary mammalian cells.
@en
type
label
Nuclear organization of DNA replication in primary mammalian cells.
@en
prefLabel
Nuclear organization of DNA replication in primary mammalian cells.
@en
P2093
P2860
P356
P1433
P1476
Nuclear organization of DNA replication in primary mammalian cells
@en
P2093
P2860
P304
P356
10.1101/GAD.842600
P577
2000-11-01T00:00:00Z