Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication. - Wikidata - awgldk - TriplyDB

Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication.

Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication.

http://www.wikidata.org/entity/Q40445488

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Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway Stress Beyond Translation: Poxviruses and More mTOR Regulation of Lymphoid Cells in Immunity to Pathogens Mechanisms of cancer cell killing by the adenovirus E4orf4 protein The human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinase The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response Structure- and modeling-based identification of the adenovirus E4orf4 binding site in the protein phosphatase 2A B55α subunit Adenovirus E4orf4 hijacks rho GTPase-dependent actin dynamics to kill cells: a role for endosome-associated actin assembly.Localization and importance of the adenovirus E4orf4 protein during lytic infection Analysis by live imaging of effects of the adenovirus E4orf4 protein on passage through mitosis of H1299 tumor cells.Baculovirus-mediated gene transfer and recombinant protein expression do not interfere with insulin dependent phosphorylation of PKB/Akt in human SHSY-5Y and C3A cells Preclinical Safety Studies of Enadenotucirev, a Chimeric Group B Human-Specific Oncolytic Adenovirus The cytosolic tail of the Golgi apyrase Ynd1 mediates E4orf4-induced toxicity in Saccharomyces cerevisiae.Hepatitis C virus NS5A activates the mammalian target of rapamycin (mTOR) pathway, contributing to cell survival by disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTOR A plant virus movement protein regulates the Gcn2p kinase in budding yeast.Genetic identification of adenovirus type 5 genes that influence viral spread.The battle over mTOR: an emerging theatre in host-pathogen immunity Hijacking Dlg1 for oncogenic phosphatidylinositol 3-kinase activation in human epithelial cells is a conserved mechanism of human adenovirus E4-ORF1 proteins.Effects of the deletion of early region 4 (E4) open reading frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on virus-host cell interaction, transgene expression, and immunogenicity of replicating adenovirus HIV vaccine vectors.Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses.Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38.Cell polarity proteins: common targets for tumorigenic human viruses.Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity.HPV-18 E6 mutants reveal p53 modulation of viral DNA amplification in organotypic cultures.Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene.Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway.E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirus Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis.The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.Tinkering with translation: protein synthesis in virus-infected cells.Make yourself at home: viral hijacking of the PI3K/Akt signaling pathway.Metabolic reprogramming: a hallmark of viral oncogenesis.(13) C-metabolic flux analysis of human adenovirus infection: Implications for viral vector production.Inhibition of mTORC1 inhibits lytic replication of Epstein-Barr virus in a cell-type specific manner.Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication.Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation.Impact of Autophagy in Oncolytic Adenoviral Therapy for Cancer.

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Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication.

http://www.wikidata.org/entity/Q40445488

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Adenoviral proteins mimic nutr ...... pathway for viral replication.

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type

label

Adenoviral proteins mimic nutr ...... pathway for viral replication.

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Adenoviral proteins mimic nutr ...... pathway for viral replication.

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SJ.EMBOJ.7600597

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The EMBO Journal

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Adenoviral proteins mimic nutr ...... pathway for viral replication.

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Bridget Bagus

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Clodagh O'Shea

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Conrado Soria

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David Stokoe

http://www.w3.org/2001/XMLSchema#string

Frank McCormick

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Jerry Shen

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Kristina Klupsch

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Serah Choi

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P2860

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

A simplified system for generating recombinant adenoviruses

TSC2 mediates cellular energy response to control cell growth and survival

Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.

Creation of human tumour cells with defined genetic elements

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

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1211-1221

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6

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24

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2005-03-03T00:00:00Z

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7958949

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15775987

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556401

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