Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. - Wikidata - awgldk - TriplyDB

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

http://www.wikidata.org/entity/Q40448208

about

Angiocrine functions of organ-specific endothelial cells Megakaryocytes, malignancy and bone marrow vascular niches The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice.Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells.Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.Disruption of thrombospondin-2 accelerates ischemic fracture healing.Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2.Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.The thrombospondins.Matricellular proteins in cardiac adaptation and disease.Thrombopoietic cells and the bone marrow vascular niche.Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis.The extracellular matrix and blood vessel formation: not just a scaffold.Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis CD47: a new target in cardiovascular therapy.Commercial development of cell-based therapeutics: strategic considerations along the drug to tissue spectrum.The role of thrombospondins in wound healing, ischemia, and the foreign body reaction.Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.Platelets in pulmonary hypertension: a causative role or a simple association?The functional role of platelets in the regulation of angiogenesis.Regulation of hematopoietic stem cells in the niche.Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs.The sticky truth about angiogenesis and thrombospondins.Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissues Functional heterogeneity of the bone marrow vascular niche Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.Role of thrombospondin-2 in murine adipose tissue angiogenesis and development.Expression of VEGF and Cox-2 in Patients with Esophageal Squamous Cell Carcinoma Thrombospondin-1 and disease progression in dysferlinopathy.A novel molecular marker of prognosis in colorectal cancer: Vasohibin-1.Unraveling the Role of Angiogenesis in Cancer Ecosystems.

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Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

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Aaron J Marcus

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Andrea T Hooper

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David K Jin

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Fan Zhang

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Hans-Georg Kopp

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Isabelle Petit

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M Johan Broekman

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Min Luo

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Paul Bornstein

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Scott T Avecilla

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P2860

Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides

A thrombin-sensitive protein of human platelet membranes

Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis

Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity

Megakaryocytes require thrombospondin-2 for normal platelet formation and function

The functional role of blood platelet components in angiogenesis

Platelet-released phospholipids link haemostasis and angiogenesis.

Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysis.

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.

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revascularization

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