Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1.
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Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells.Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.RUNX3 mediates suppression of tumor growth and metastasis of human CCRCC by regulating cyclin related proteins and TIMP-1.Gene therapy for gastric cancer: is it promising?Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.RUNX3 reverses cisplatin resistance in esophageal squamous cell carcinoma via suppression of the protein kinase B pathway.RUNX3 regulates vimentin expression via miR-30a during epithelial-mesenchymal transition in gastric cancer cellsTranscriptional regulation of MDR-1 by HOXC6 in multidrug-resistant cells.MGr1-Ag/37LRP promotes growth and proliferation of gastric cancer in vitro and in vivo.MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3.Loss of runt-related transcription factor 3 induces gemcitabine resistance in pancreatic cancer.CacyBP/SIP enhances multidrug resistance of pancreatic cancer cells by regulation of P-gp and Bcl-2.Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and p38 MAPK pathways in gastric epithelial cell.RUNX3-mediated transcriptional inhibition of Akt suppresses tumorigenesis of human gastric cancer cells.Runx3 suppresses gastric cancer metastasis through inactivation of MMP9 by upregulation of TIMP-1.Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells.A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax.MicroRNA-130a regulates autophagy of endothelial progenitor cells through Runx3.Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.Runx3 Expression Inhibits Proliferation and Distinctly Alters mRNA Expression of Bax in AGS and A549 Cancer Cells.Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.Epigenetic inactivation of RUNX3 in colorectal cancer.Multidrug resistance in hepatic cancer stem cells: the emerging role of miRNAs.Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.Expression levels of the runt-related transcription factor 1 and 3 genes in the development of acute myeloid leukemia.
P2860
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P2860
Tumor suppressor gene Runx3 sensitizes gastric cancer cells to chemotherapeutic drugs by downregulating Bcl-2, MDR-1 and MRP-1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Tumor suppressor gene Runx3 se ...... lating Bcl-2, MDR-1 and MRP-1.
@en
type
label
Tumor suppressor gene Runx3 se ...... lating Bcl-2, MDR-1 and MRP-1.
@en
prefLabel
Tumor suppressor gene Runx3 se ...... lating Bcl-2, MDR-1 and MRP-1.
@en
P2093
P356
P1476
Tumor suppressor gene Runx3 se ...... lating Bcl-2, MDR-1 and MRP-1.
@en
P2093
Changcun Guo
Daiming Fan
Liping Yao
P304
P356
10.1002/IJC.20919
P577
2005-08-01T00:00:00Z