Hypothesis: glutaminyl cyclase inhibitors decrease risks of Alzheimer's disease and related dementias.

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Hypothesis: glutaminyl cyclase inhibitors decrease risks of Alzheimer's disease and related dementias.

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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Hypothesis: glutaminyl cyclase ...... disease and related dementias.

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Hypothesis: glutaminyl cyclase ...... disease and related dementias.

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Hypothesis: glutaminyl cyclase ...... disease and related dementias.

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P1476

Hypothesis: glutaminyl cyclase ...... disease and related dementias.

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P2093

Benjamin A Bensadon

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Charles H Hennekens

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J Michael Gaziano

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Robert Zivin

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P2860

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β.

Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial.

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease

Passive immunization against pyroglutamate-3 amyloid-β reduces plaque burden in Alzheimer-like transgenic mice: a pilot study.

The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species.

Alzheimer's failure raises questions about disease-modifying strategies.

Glutaminyl cyclases display significant catalytic proficiency for glutamyl substrates.

P304

1245-1248

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P31

scholarly article

P356

10.1586/14737175.2015.1088784

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P433

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P478

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P577

2015-10-08T00:00:00Z

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P5875

282765070

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P698

26450764

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P921

Alzheimer's disease