Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt.
about
The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal differentiationStimulatory versus suppressive effects of GM-CSF on tumor progression in multiple cancer typesHIV-1 Nef induces p47(phox) phosphorylation leading to a rapid superoxide anion release from the U937 human monoblastic cell line.Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state.Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co-morbiditiesFibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture studyGranulocyte-macrophage colony-stimulating factor antibody suppresses microglial activity: implications for anti-inflammatory effects in Alzheimer's disease and multiple sclerosisSrc family kinases participate in the regulation of encephalomyocarditis virus-induced cyclooxygenase-2 expression by macrophagesMechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathwaysMultiple host kinases contribute to Akt activation during Salmonella infection.Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis.Population control of resident and immigrant microglia by mitosis and apoptosis.Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB.The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3beta and nuclear factor-kappaB to foster endogenous microglial cell protection.Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral responseHematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML.HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND.Young microglia restore amyloid plaque clearance of aged microglia.Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators.Cellular reservoirs of HIV-1 and their role in viral persistence.Targeting the JAK2/STAT3 axis in Alzheimer's disease.Curing HIV: Pharmacologic approaches to target HIV-1 latency.Screen and analysis of key disease genes for precancerous lesions of oral buccal mucosa induced by DMBA in golden hamsters.Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrestEvidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genesHistone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes.TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS.TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.Proliferation of microglial cells induced by 1-methyl-4-phenylpyridinium in mesencephalic cultures results from an astrocyte-dependent mechanism: role of granulocyte macrophage colony-stimulating factor.Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling.Expression of two temporally distinct microglia-related gene clusters after spinal cord injury.Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors.Maintenance of Stemlike Glioma Cells and Microglia in an Organotypic Glioma Slice Model.
P2860
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P2860
Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Inhibition of granulocyte-macr ...... phatidylinositol 3-kinase/Akt.
@en
type
label
Inhibition of granulocyte-macr ...... phatidylinositol 3-kinase/Akt.
@en
prefLabel
Inhibition of granulocyte-macr ...... phatidylinositol 3-kinase/Akt.
@en
P2093
P1476
Inhibition of granulocyte-macr ...... phatidylinositol 3-kinase/Akt.
@en
P2093
Hyeon-Sook Suh
Mee-Ohk Kim
Sunhee C Lee
P304
P356
10.4049/JIMMUNOL.174.5.2712
P407
P577
2005-03-01T00:00:00Z