PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.
about
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasisA novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalizationCrosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasisFibroblasts, an inconspicuous but essential player in colon cancer development and progressionInfluence of Immune Myeloid Cells on the Extracellular Matrix During Cancer MetastasisTissue factor, protease activated receptors and pathologic heart remodellingMatrix metalloproteinases in stem cell regulation and cancerActivation of blood coagulation in cancer: implications for tumour progressionUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerCancer-associated fibroblasts in digestive tumorsTurning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug developmentEndothelial protein C receptor function in murine and human breast cancer developmentDevelopmental role of zebrafish protease-activated receptor 1 (PAR1) in the cardio-vascular systemRole and therapeutic potential of G-protein coupled receptors in breast cancer progression and metastasesThrombin receptors and their antagonists: an update on the patent literatureG-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significanceProteinases, their receptors and inflammatory signalling: the Oxford South Parks Road connectionMatrix metalloproteinases: regulators of the tumor microenvironmentCancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages.Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61.MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formationIn vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots.Predictive diagnosis of the risk of breast cancer recurrence after surgery by single-particle quantum dot imaging.Data perturbation independent diagnosis and validation of breast cancer subtypes using clustering and patterns.Tissue factor and PAR2 signaling in the tumor microenvironmentThe activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion.Function of EWS-POU5F1 in sarcomagenesis and tumor cell maintenance.Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophyThe Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growthParstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis.GPCRs and cancerMultifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative DisordersGbetagamma signaling promotes breast cancer cell migration and invasion.Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer.Cancer-associated fibroblasts derived from EGFR-TKI-resistant tumors reverse EGFR pathway inhibition by EGFR-TKIs.Fibroblast heterogeneity in the cancer wound.Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1).
P2860
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P2860
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
PAR1 is a matrix metalloprotea ...... enesis of breast cancer cells.
@en
type
label
PAR1 is a matrix metalloprotea ...... enesis of breast cancer cells.
@en
prefLabel
PAR1 is a matrix metalloprotea ...... enesis of breast cancer cells.
@en
P2093
P1433
P1476
PAR1 is a matrix metalloprotea ...... enesis of breast cancer cells.
@en
P2093
Anika Agarwal
Athan Kuliopulos
Lidija Covic
Sheida Sherifi
Suzanne Jacques
P304
P356
10.1016/J.CELL.2004.12.018
P407
P577
2005-02-01T00:00:00Z