Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase. - Wikidata - awgldk - TriplyDB

Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

http://www.wikidata.org/entity/Q40469680

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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells.TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer: Normalization, Not Destruction TGF-β signaling via TAK1 pathway: role in kidney fibrosis Regulation of autophagy by TGF-β: emerging role in kidney fibrosis TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function NetSlim: high-confidence curated signaling maps TGF-beta-induced epithelial to mesenchymal transition Non-Smad pathways in TGF-beta signaling Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cells Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta.ActRIIA and BMPRII Type II BMP receptor subunits selectively required for Smad4-independent BMP7-evoked chemotaxis TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness.TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells An intracameral injection of antigen induces in situ chemokines and cytokines required for the generation of circulating immunoregulatory monocytes.Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4 Regulation of TGF-β1-Induced Pro-Apoptotic Signaling by Growth Factor Receptors and Extracellular Matrix Receptor Integrins in the Liver.The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling.MicroRNAs and the glomerulus Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis.MicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy.Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer MiR-181b regulates cisplatin chemosensitivity and metastasis by targeting TGFβR1/Smad signaling pathway in NSCLC.Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells.TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease.BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells.TGF-β signaling in the kidney: profibrotic and protective effects Tumor-stromal interactions in pancreatic cancer Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling

P2860

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P2860

Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

http://www.wikidata.org/entity/Q40469680

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Type I transforming growth fac ...... phosphatidylinositol 3-kinase.

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type

label

Type I transforming growth fac ...... phosphatidylinositol 3-kinase.

@en

prefLabel

Type I transforming growth fac ...... phosphatidylinositol 3-kinase.

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P1433

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Journal of Biological Chemistry

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Type I transforming growth fac ...... phosphatidylinositol 3-kinase.

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P2093

Carlos L Arteaga

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Incheol Shin

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Jae Youn Yi

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P2860

TGF-beta signal transduction

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

Untangling the ErbB signalling network

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Signaling by distinct classes of phosphoinositide 3-kinases

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors

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10870-10876

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scholarly article

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10.1074/JBC.M413223200

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11

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280

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2005-01-18T00:00:00Z

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8074465

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15657037

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