A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.
about
Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cellsN-glycans and glycosylphosphatidylinositol-anchor act on polarized sorting of mouse PrP(C) in Madin-Darby canine kidney cells.Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesionProteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion proteinPrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK CellsMolecular basis of cerebral neurodegeneration in prion diseases.alpha-Helical domains promote translocation of intrinsically disordered polypeptides into the endoplasmic reticulumResidues surrounding the glycosylphosphatidylinositol anchor attachment site of PrP modulate prion infection: insight from the resistance of rabbits to prion disease.Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro.The prion-like protein Doppel enhances ovine spermatozoa fertilizing ability.Cellular Prion Protein in the Bovine Mammary Gland Is Selectively Expressed in Active Lactocytes
P2860
Q33675107-42D61D07-ECE4-4202-9CA4-7E6D6F9601F1Q34023780-0EC93D59-B0DB-432C-A01A-A93833576A7FQ34922583-E04240BB-3E37-4EA6-8614-31D3BFDC2CDAQ35311053-DB2AE743-DEC5-49FA-8C1B-6B549261BB8DQ36070581-70423BF7-8CD4-4892-965A-95B986BD5F87Q36731464-31EA28DB-7CF3-4388-901A-66219E608813Q39832083-7C416FAD-7797-4D43-81FF-A46C36136FF0Q42733855-DF4E6387-AA2D-41C1-BBB8-EE0DAB963FBCQ42976640-C4D0E685-6C71-410E-A396-FEB43A86BB1DQ46916908-B49AC154-EC37-463F-A0ED-30E21EEBB611Q48667451-96CC703F-3242-4C60-84CC-CE1423436833Q57375525-617CDB07-5AC8-4E00-80E1-16C73DB5013F
P2860
A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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name
A pathogenic PrP mutation and ...... sorting of the prion protein.
@en
type
label
A pathogenic PrP mutation and ...... sorting of the prion protein.
@en
prefLabel
A pathogenic PrP mutation and ...... sorting of the prion protein.
@en
P2860
P50
P356
P1476
A pathogenic PrP mutation and ...... sorting of the prion protein.
@en
P2093
Armgard Uelhoff
Jörg Tatzelt
P2860
P304
P356
10.1074/JBC.C400560200
P407
P577
2004-12-21T00:00:00Z