AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.
about
Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartmentsFunctions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomesInteractions of the proteins of neuronal ceroid lipofuscinosis: clues to functionExpression and lysosomal targeting of CLN7, a major facilitator superfamily transporter associated with variant late-infantile neuronal ceroid lipofuscinosisPhosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles.A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cellsThe juvenile Batten disease protein, CLN3, and its role in regulating anterograde and retrograde post-Golgi trafficking.Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3.Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.The clathrin adaptor complex AP-1 binds HIV-1 and MLV Gag and facilitates their budding.Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses.Subcellular Trafficking of Mammalian Lysosomal Proteins: An Extended View.Detailed Clinical Phenotype and Molecular Genetic Findings in CLN3-Associated Isolated Retinal Degeneration.The polymorphic HCMV glycoprotein UL20 is targeted for lysosomal degradation by multiple cytoplasmic dileucine motifs.Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways.The cytoplasmic tail of glycoprotein M (gpUL100) expresses trafficking signals required for human cytomegalovirus assembly and replicationThe fission yeast model for the lysosomal storage disorder Batten disease predicts disease severity caused by mutations in CLN3.Lack of specificity of antibodies raised against CLN3, the lysosomal/endosomal transmembrane protein mutated in juvenile Batten disease.Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis.C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes.
P2860
Q24302244-6D1CDA5C-7F32-4FCD-AADF-77F2F8949D3AQ24323356-87CF5797-8C51-44AB-ADCE-0FC5B7E9FEFEQ28289653-33C6639A-2C4C-4A6E-AA10-C72E57308AB8Q28589863-2BA70E27-576B-4BE8-BA5F-08CAE067A5D0Q33911122-F01C0D76-E6A1-48B9-983E-93987D4E44C0Q34014206-04F2D2E1-8D13-4360-93A4-F528D9543251Q34271805-8D553DB3-F8E2-41ED-9687-0B530583B902Q34772470-2EC9D088-6B3A-422F-86BA-FEADF3C09748Q34805162-15C9D883-E24D-4F1F-A127-2F021DF02C96Q35942353-1BCB0ADF-329B-47E6-AF38-BA1DA96582CAQ36302113-7BF0C9BA-77CA-41FE-BB4E-12D229D2F1DCQ37944570-481E00CC-807E-4C48-B936-F361E2C62069Q39063017-68DDE57B-0938-4856-83F1-E35560B58F8DQ39329067-82EBE4F6-1321-42A5-BE3A-07714C678B10Q39521419-78399CD0-D19E-4E4B-B308-CDB831E7CC00Q39912954-E75C3979-DE1B-4799-AAC6-C2181975FBFEQ41832051-4589F84F-7E05-484C-96BD-0F0B31D88FE6Q42040450-BD8D2FC4-22FE-4D76-BC27-519BC82041CEQ47134547-059D8F2C-EB13-44F5-A0E8-1564E65D4483Q48465441-CD473790-78CB-4579-B54A-9C40CD17546CQ55043107-D547ED77-CF9D-4B2A-A72B-0B2B0324162C
P2860
AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
AP-1 and AP-3 facilitate lysos ...... CLN3 via its dileucine motif.
@en
type
label
AP-1 and AP-3 facilitate lysos ...... CLN3 via its dileucine motif.
@en
prefLabel
AP-1 and AP-3 facilitate lysos ...... CLN3 via its dileucine motif.
@en
P2093
P2860
P356
P1476
AP-1 and AP-3 facilitate lysos ...... CLN3 via its dileucine motif.
@en
P2093
Aija Kyttälä
Anu Jalanko
J Paul Luzio
Kristiina Yliannala
Peter Schu
P2860
P304
10277-10283
P356
10.1074/JBC.M411862200
P407
P577
2004-12-13T00:00:00Z