Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
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Signaling in T cells - is anything the m(a)TOR with the picture(s)?Immunometabolism of regulatory T cellsDynamic Metabolism in Immune ResponseGlycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation.ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production.From Krebs to clinic: glutamine metabolism to cancer therapy.Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota.Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond.GLUT1 and ASCT2 as Predictors for Prognosis of Hepatocellular CarcinomaCell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions.Amino acid auxotrophy as a system of immunological control nodes.Nutrient and Metabolic Sensing in T Cell Responses.Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.Metabolome alterations in severe critical illness and vitamin D status.Prevention and treatment of cancers by immune modulating nutrients.Role of Metabolism in the Immunobiology of Regulatory T Cells.Metabolic regulation of inflammation.Metabolic Hallmarks of Tumor and Immune Cells in the Tumor MicroenvironmentCancer cell metabolism: the essential role of the nonessential amino acid, glutamine.Insight on the impacts of free amino acids and their metabolites on the immune system from a perspective of inborn errors of amino acid metabolism.Restricting Glutamine or Glutamine-Dependent Purine and Pyrimidine Syntheses Promotes Human T Cells with High FOXP3 Expression and Regulatory Properties.Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes.Metabolic orchestration of T lineage differentiation and function.Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery.Glutamine supplementation suppresses herpes simplex virus reactivation.Augmentation of glycolytic metabolism by meclizine is indispensable for protection of dorsal root ganglion neurons from hypoxia-induced mitochondrial compromiseT Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections.Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells.Glutamine Synthetase: Localization Dictates Outcome.The spectrum of T cell metabolism in health and disease.Regulatory T Cell Metabolism in the Hepatic Microenvironment.Navigating T-Cell Immunometabolism in Transplantation.CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.Influence of Inflammation in the Process of T Lymphocyte Differentiation: Proliferative, Metabolic, and Oxidative Changes.GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress.Metabolic Adaptations of CD4+ T Cells in Inflammatory Disease.Chytridiomycosis causes catastrophic organism-wide metabolic dysregulation including profound failure of cellular energy pathways.The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.
P2860
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P2860
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Glutamine-dependent α-ketoglut ...... regulatory T cell generation.
@en
type
label
Glutamine-dependent α-ketoglut ...... regulatory T cell generation.
@en
prefLabel
Glutamine-dependent α-ketoglut ...... regulatory T cell generation.
@en
P2093
P2860
P50
P1433
P1476
Glutamine-dependent α-ketoglut ...... regulatory T cell generation.
@en
P2093
Carmen Yong
Cédric Mongellaz
Dorota Klysz
Gaspard Cretenet
Jochen Huehn
Maria I Matias
Naomi Taylor
Natalie Surh
Philippe A Robert
Sandrina Kinet
P2860
P356
10.1126/SCISIGNAL.AAB2610
P577
2015-09-29T00:00:00Z