about
Imaging mass spectrometry for the precise design of antibody-drug conjugates.Discovery of an uncovered region in fibrin clots and its clinical significance.Antitumor effect of antitissue factor antibody-MMAE conjugate in human pancreatic tumor xenograftsSynthesis of monoglucosylated high-mannose-type dodecasaccharide, a putative ligand for molecular chaperone, calnexin, and calreticulin.Mycothiol synthesis by an anomerization reaction through endocyclic cleavage.Increased expression of protein C-mannosylation in the aortic vessels of diabetic Zucker rats.Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease.Development of Antibody-Drug Conjugates Using DDS and Molecular Imaging.Phenyl 2-amino-N,6-O-dibenzyl-2,3-N,O-carbonyl-2-de-oxy-1-thio-β-d-glucopyran-oside.Electrochemical generation of 2,3-oxazolidinone glycosyl triflates as an intermediate for stereoselective glycosylation.C-Mannosylated peptides derived from the thrombospondin type 1 repeat interact with Hsc70 to modulate its signaling in RAW264.7 cells.Preparation of glycosylated amino acid derivatives for glycoprotein synthesis by in vitro translation system.[Development of novel methodology for rapid conjugated oligosaccharide synthesis].On-resin real-time reaction monitoring of solid-phase oligosaccharide synthesis.Total synthesis of mannosyl tryptophan and its derivatives.Sulfonylcarbamate as a versatile and unique hydroxy-protecting group: a protecting group stable under severe conditions and labile under mild conditions.Alpha- and beta-glycosyl sulfonium ions: generation and reactivity.Systematic synthesis of bisubstrate-type inhibitors of N-acetylglucosaminyltransferases.Tag-reporter strategy for facile oligosaccharide synthesis on polymer support.Enrichment and characterization of a bacterial mixture capable of utilizing C-mannosyl tryptophan as a carbon source.Development of ADCs Using Molecular Imaging.Pyranosides with 2,3-trans carbamate groups: exocyclic or endocyclic cleavage reaction?Significant substituent effect on the anomerization of pyranosides: mechanism of anomerization and synthesis of a 1,2-cis glucosamine oligomer from the 1,2-trans anomer.Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue.Endocyclic cleavage in glycosides with 2,3-trans cyclic protecting groups.Evidence for endocyclic cleavage of conformationally restricted glycopyranosides.Acceptor range of endo-β-N-acetylglucosaminidase mutant endo-CC N180H: from monosaccharide to antibody.Chemotherapy payload of anti-insoluble fibrin antibody-drug conjugate is released specifically upon binding to fibrinS-Phenyl 4,6-O-benzylidene-2,3-O-carbonyl-1-thia-α-D-mannopyranosideA novel assay for detection and quantification of C-mannosyl tryptophan in normal or diabetic miceC-Mannosylation: A Modification on Tryptophan in Cellular ProteinsSynthesis of N-linked pentasaccharides with isomeric glycosidic linkageWang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: polymer-supported glycosyl donorSolid-phase oligosaccharide synthesis and related technologiesN-benzyl-2,3-oxazolidinone as a glycosyl donor for selective alpha-glycosylation and one-pot oligosaccharide synthesis involving 1,2-cis-glycosylationSynthesis of a natural oligosaccharide antibiotic active against Helicobacter pyloriPolymer-supported oligosaccharide synthesis using ultrafiltration methodologyDivergent synthesis of sialylated glycan chains: combined use of polymer support, resin capture-release, and chemoenzymatic strategiesGlycosyl sulfonium ions as storable intermediates for glycosylationsNew concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Shino Manabe
@ast
Shino Manabe
@en
Shino Manabe
@es
Shino Manabe
@nl
Shino Manabe
@sl
type
label
Shino Manabe
@ast
Shino Manabe
@en
Shino Manabe
@es
Shino Manabe
@nl
Shino Manabe
@sl
prefLabel
Shino Manabe
@ast
Shino Manabe
@en
Shino Manabe
@es
Shino Manabe
@nl
Shino Manabe
@sl
P1053
F-2334-2014
P106
P1153
7102875651
P31
P3829
P496
0000-0002-2763-1414