Mammary ECM composition and function are altered by reproductive state.
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Keystone symposium: the role of microenvironment in tumor induction and progression, Banff, Canada, 5-10 February 2005Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshopDeciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast CancerAlternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across speciesAn in-solution ultrasonication-assisted digestion method for improved extracellular matrix proteome coverageThe MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium.Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypesTransforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo.Quantitative analysis of three-dimensional human mammary epithelial tissue architecture reveals a role for tenascin-C in regulating c-met function.Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissueClusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response.The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesisA strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.Cell-matrix interactions in mammary gland development and breast cancerPostpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progressionPregnancy-associated breast cancer and metastasis.Mammary gland reprogramming: metalloproteinases couple form with functionRat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis.Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progressionStromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma.Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis.Stringent requirement for spatial arrangement of extracellular matrix in supporting cell morphogenesis and differentiation.Mammary gland involution as an immunotherapeutic target for postpartum breast cancer.Gene expression analysis of in vitro cocultures to study interactions between breast epithelium and stroma.Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s).Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models.Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.Microenvironmental control of the breast cancer cell cycle.Mapping of mechanical strains and stresses around quiescent engineered three-dimensional epithelial tissues.Breast cancer-derived extracellular vesicles stimulate myofibroblast differentiation and pro-angiogenic behavior of adipose stem cells.Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization.The extracellular matrix as an adhesion checkpoint for mammary epithelial function.ATG proteins mediate efferocytosis and suppress inflammation in mammary involution.Three-dimensional culture of human breast epithelial cells: the how and the why.Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epitheliumCollagen architecture in pregnancy-induced protection from breast cancerMammary involution and breast cancer risk: transgenic models and clinical studies.Macrophages in breast cancer: do involution macrophages account for the poor prognosis of pregnancy-associated breast cancer?
P2860
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P2860
Mammary ECM composition and function are altered by reproductive state.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Mammary ECM composition and function are altered by reproductive state.
@en
type
label
Mammary ECM composition and function are altered by reproductive state.
@en
prefLabel
Mammary ECM composition and function are altered by reproductive state.
@en
P2093
P2860
P356
P1476
Mammary ECM composition and function are altered by reproductive state.
@en
P2093
Mark Kaeck
Pepper Schedin
Shauntae McDaniel
Terry Mitrenga
P2860
P304
P356
10.1002/MC.20058
P577
2004-12-01T00:00:00Z