The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation.
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Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous Fibrosis.Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathwaysAreca nut components affect COX-2, cyclin B1/cdc25C and keratin expression, PGE2 production in keratinocyte is related to reactive oxygen species, CYP1A1, Src, EGFR and Ras signaling.Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activationGene expression profile of esophageal cancer in North East India by cDNA microarray analysis.Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells.Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells.Regional protein levels of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey brain as a function of agep-Cresol affects reactive oxygen species generation, cell cycle arrest, cytotoxicity and inflammation/atherosclerosis-related modulators production in endothelial cells and mononuclear cells.Signaling mechanism of thrombin-induced gingival fibroblast-populated collagen gel contraction.Status of epigenetic chromatin modification enzymes and esophageal squamous cell carcinoma risk in northeast Indian population.Characterization of a Novel Dermal Fibrosis Model Induced by Areca Nut Extract that Mimics Oral Submucous FibrosisEffect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells.Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma.Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance.Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling.Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density.Interleukin-6 as a therapy target in oral squamous carcinoma.Areca nut contributes to oral malignancy through facilitating the conversion of cancer stem cells.Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro.Panax notoginseng saponins inhibit areca nut extract-induced oral submucous fibrosis in vitro.Toxicity of areca nut ingredients: activation of CHK1/CHK2, induction of cell cycle arrest, and regulation of MMP-9 and TIMPs production in SAS epithelial cells.Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells.Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells.Arecoline increases basic fibroblast growth factor but reduces expression of IL-1, IL-6, G-CSF and GM-CSF in human umbilical vein endothelium.Effect of triethylene glycol dimethacrylate on the cytotoxicity, cyclooxygenase-2 expression and prostanoids production in human dental pulp cells.Prostaglandin F(2alpha) stimulates MEK-ERK signalling but decreases the expression of alkaline phosphatase in dental pulp cells.Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts.Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.Arecoline is cytotoxic for human endothelial cells.Enhancing effects of areca nut extracts on the production of interleukin-6 and interleukin-8 by peripheral blood mononuclear cells.Arecoline-stimulated placenta growth factor production in gingival epithelial cells: modulation by curcumin.Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2.Relationship of Oxidative Stress, Inflammation, and the Risk of Metabolic Syndrome in Patients with Oral Cancer.
P2860
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P2860
The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The induction of prostaglandin ...... gulated by MEK/ERK activation.
@en
type
label
The induction of prostaglandin ...... gulated by MEK/ERK activation.
@en
prefLabel
The induction of prostaglandin ...... gulated by MEK/ERK activation.
@en
P2093
P2860
P50
P356
P1476
The induction of prostaglandin ...... egulated by MEK/ERK activation
@en
P2093
Hsiao-Hwa Chang
Hui-Lin Wu
Jang-Jaer Lee
Liang-Jiunn Hahn
Mei-Chi Chang
Po-Hsuen Lee
P2860
P304
50676-50683
P356
10.1074/JBC.M404465200
P407
P577
2004-09-16T00:00:00Z