Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
about
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancerProgress and problems with the use of suicide genes for targeted cancer therapyCharacterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPTAntitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene.Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancerEnhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.Purine nucleoside phosphorylase targeted by annexin v to breast cancer vasculature for enzyme prodrug therapy.Gene therapy and targeted toxins for glioma.Mycoplasmas and cancer: focus on nucleoside metabolismPhase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumorsIn vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.Genetic strategies for brain tumor therapy.Novel gene-directed enzyme prodrug therapies against prostate cancer.Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancerDevelopment of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues.Armed and targeted measles virus for chemovirotherapy of pancreatic cancer.PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy.Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening.Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.Tumor-specific suicide gene therapy for hepatocellular carcinoma by transcriptionally targeted retroviral replicating vectors.Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.Advances in the mechanisms of action of cancer-targeting oncolytic viruses.Gene therapy and targeted toxins for glioma
P2860
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P2860
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Excellent in vivo bystander ac ...... nucleoside phosphorylase gene.
@en
type
label
Excellent in vivo bystander ac ...... nucleoside phosphorylase gene.
@en
prefLabel
Excellent in vivo bystander ac ...... nucleoside phosphorylase gene.
@en
P2093
P1433
P1476
Excellent in vivo bystander ac ...... nucleoside phosphorylase gene.
@en
P2093
Bryan A Moore
Dana N Levasseur
Eric J Sorscher
Jeong S Hong
John A Secrist
Paula W Allan
Sylvia A McPherson
Tim M Townes
William B Parker
P304
P356
10.1158/0008-5472.CAN-04-0012
P407
P577
2004-09-01T00:00:00Z