Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor.
about
A novel role of Sprouty 2 in regulating cellular apoptosisRole of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapyDesign and synthesis of sulfamoyl benzoic acid analogues with subnanomolar agonist activity specific to the LPA2 receptor.Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase.Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acidThe autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury.Mitigation of radiation injury by selective stimulation of the LPA(2) receptorVirtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function.
P2860
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P2860
Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Optimal lysophosphatidic acid- ...... dermal growth factor receptor.
@en
type
label
Optimal lysophosphatidic acid- ...... dermal growth factor receptor.
@en
prefLabel
Optimal lysophosphatidic acid- ...... dermal growth factor receptor.
@en
P2093
P2860
P356
P1476
Optimal lysophosphatidic acid- ...... idermal growth factor receptor
@en
P2093
De-An Wang
Gabor Tigyi
Helen Poppleton
Leonard R Johnson
Natalia Makarova
Tarun B Patel
Wenlin Deng
Yoriko Shinozuka
P2860
P304
47871-47880
P356
10.1074/JBC.M405443200
P407
P577
2004-09-10T00:00:00Z