Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
about
SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancerA potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinomaMammary stem cells, self-renewal pathways, and carcinogenesisHedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancersActivation of the hedgehog pathway in advanced prostate cancerTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsHedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic SignalingClinical Implications of Hedgehog Pathway Signaling in Prostate CancerThe Role of Hedgehog Signaling in Tumor Induced Bone DiseaseThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerRoles for Hedgehog signaling in adult organ homeostasis and repairCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsHedgehog signaling pathway in ovarian cancerPolymer-drug conjugates: origins, progress to date and future directionsContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyMolecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsHedgehog pathway activity in the LADY prostate tumor modelCyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastomaHedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cellsHedgehog signaling and the Gli code in stem cells, cancer, and metastasesCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsIn vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehogHedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate CancerBiography of Philip A. BeachyThe impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasisChemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathwayalphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathwayLow-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new boneSelf-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathwaysSnail induction is an early response to Gli1 that determines the efficiency of epithelial transformationCompensatory pathways induced by MEK inhibition are effective drug targets for combination therapy against castration-resistant prostate cancerAndrogen deprivation by activating the liver X receptor.Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts.Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladderSonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.
P2860
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P2860
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
@en
type
label
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
@en
prefLabel
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
@en
P2093
P356
P1433
P1476
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
@en
P2093
Anirban Maitra
Dale Gardner
David M Berman
G Steven Bova
John T Isaacs
Nadia Abdallah
Philip A Beachy
Sunil S Karhadkar
Surajit Dhara
P2888
P304
P356
10.1038/NATURE02962
P407
P577
2004-09-12T00:00:00Z
P5875
P6179
1005835950