A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
about
Organic chemistry. A data-intensive approach to mechanistic elucidation applied to chiral anion catalysis.Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayersX-ray crystal structure of teicoplanin A₂-2 bound to a catalytic peptide sequence via the carrier protein strategy.Opportunities for merging chemical and biological synthesisLabel-assisted mass spectrometry for the acceleration of reaction discovery and optimizationMultidimensional reaction screening for photochemical transformations as a tool for discovering new chemotypes.Using non-enzymatic chemistry to influence microbial metabolismEnzyme immunoassays as screening tools for catalysts and reaction discovery.Discovery of an α-amino C-H arylation reaction using the strategy of accelerated serendipity.New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries.Suzuki-Miyaura cross-coupling optimization enabled by automated feedback.Metabolic engineering: the ultimate paradigm for continuous pharmaceutical manufacturing.Experiment and computation: a combined approach to study the reactivity of palladium complexes in oxidation states 0 to IV.Contemporary screening approaches to reaction discovery and development.Snap deconvolution: An informatics approach to high-throughput discovery of catalytic reactions.Paper-Based Colorimetric Sensor System for High-Throughput Screening of C-H Borylation.NiXantphos: a deprotonatable ligand for room-temperature palladium-catalyzed cross-couplings of aryl chlorides.Reactivity mapping with electrochemical gradients for monitoring reactivity at surfaces in space and time.Implementation of Hadamard encoding for rapid multisample analysis in liquid chromatography.Pursuit of Noncovalent Interactions for Strategic Site-Selective CatalysisMini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect.Ambient arylmagnesiation of alkynes catalysed by ligandless nickel(ii).Discovery of chemoselective and biocompatible reactions using a high-throughput immunoassay screening.Ancillary ligand-free copper catalysed hydrohydrazination of terminal alkynes with NH2NH2.Identifying lead hits in catalyst discovery by screening and deconvoluting complex mixtures of catalyst components.Ni-Catalyzed regio- and stereoselective addition of arylboronic acids to terminal alkynes with a directing group tether.Fast screening of analytes for chemical reactions by reactive low-temperature plasma ionization mass spectrometry.Diverse Visible-Light-Promoted Functionalizations of Benzotriazoles Inspired by Mechanism-Based Luminescence Screening.Ultrafast chiral separations for high throughput enantiopurity analysis.Resolving a Reactive Organometallic Intermediate from Dynamic Directing Group Systems by Selective C-H Activation.The In Situ Enzymatic Screening (ISES) Approach to Reaction Discovery and Catalyst Identification.Simultaneous solvent screening and reaction optimization in microliter slugs.Reductive Cross-Coupling of Conjugated Arylalkenes and Aryl Bromides with Hydrosilanes by Cooperative Palladium/Copper Catalysis.Exploration of forbidden Povarov processes as a source of unexpected reactivity: a multicomponent Mannich-Ritter transformation.Convenient Reductive Methylation of Amines with Carbonates at Room Temperature.Accelerated Discovery in Photocatalysis using a Mechanism-Based Screening Method.Predictive and mechanistic multivariate linear regression models for reaction development.Organic Synthesis: Wherefrom and Whither? (Some Very Personal Reflections).Pushing the speed limit in enantioselective supercritical fluid chromatographyRapid Catalyst Identification for the Synthesis of the Pyrimidinone Core of HIV Integrase Inhibitors
P2860
Q30892012-8999FD85-5D53-45E2-9A5C-2B8B869F7E0DQ34101287-410AAC43-7FC9-4EC3-8B94-F459FAE8B288Q34211592-AFFC7F05-7E3C-421E-BA15-ACBFC408A2C4Q34353527-C9212959-7F55-48CB-9C41-6E6B9C94259FQ34681107-F7D4B8AF-8DEC-4D02-A89A-D80F843BDDD5Q35138910-A388FC5E-3803-4246-B3C5-ACFA767B1378Q35235881-AE517643-690E-4AE6-B7CB-F081E28FD8F1Q35576136-FAF43970-26E5-4AFE-A339-501AFA4CE481Q35697679-A1E8E704-F784-4031-87DD-8745016C1A36Q36200938-BDC01272-9A8C-4E8D-8CAB-F079E33E6629Q37441389-D4EC4407-08D3-4995-B5AB-7805C8EB641FQ38203495-73AD3FFE-CC5C-47D6-816D-53181FBD4445Q38206709-33C4DC41-EAB8-48E8-A762-453FFBE2B8E7Q38253009-0D73ECFE-5452-4BBF-93B6-A1FB1EFA166AQ38680068-A5DC8628-7032-452F-B040-D4AC596FF8A2Q38884517-676BCD3C-A255-4CE8-823A-7B2ECB6C6A36Q39495251-A30858B5-53E1-4AF9-BB17-327268286A0BQ40383013-B86F6ED9-49C2-4C66-9014-636B13EDB9FFQ40443929-09BA1CB2-ED7E-42CA-9454-06E63E5E6B2BQ42378791-15AC5045-DB97-4694-BA4A-B67248A615A9Q43086251-05FA12B7-D365-49DC-ADEB-66AFE1E374EAQ44369068-88CAC929-87CB-4883-97E7-78AABE938362Q45731462-8BE2CD76-FADB-4929-82EE-4C754749648AQ46012580-511DD8C1-122D-4A3B-B7B5-F7789A0958A3Q47097760-98A6DF71-7E40-4D2F-B035-97E8D8EEF5BEQ48103095-B4C5AB03-7497-40F2-BAE4-E73538DE238CQ48123575-42F7F635-1616-4112-B102-2524D0EA25E9Q48130667-2A1CA42D-33CA-4126-BA54-BCC57ED7EC34Q48207508-02D4D085-F597-4790-B28D-F3D6F082DC4DQ48280892-81E8F5D5-CD8C-4F06-A666-0313921E0186Q50146208-8921B426-C167-496D-B562-4A7D73534A48Q50952641-3BD89006-A7C3-4C1F-A5FC-D3D51D5BA2A8Q51370893-FD2E15A3-63A3-423E-94F5-34DBA33B4FABQ53373715-547162A9-C6BE-4FEE-AEED-5607605B67D0Q53665163-91909441-625D-4E30-9298-1D14E205AE35Q53746350-C9B1004E-09F4-40DA-90C9-9E2937F6803AQ55177601-122E7ED6-997B-4401-8497-F6FEB3AC3975Q55375468-A5A2CCA0-1787-40EB-BFF9-310144EF3E7CQ57261702-B9FFA5D3-47DC-476C-B4BE-E849419AEEEBQ57261752-AFE340F7-25AB-4941-A24B-9FAF7F28F998
P2860
A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
@en
type
label
A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
@en
prefLabel
A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
@en
P2860
P356
P1433
P1476
A simple, multidimensional approach to high-throughput discovery of catalytic reactions.
@en
P2093
Daniel W Robbins
P2860
P304
P356
10.1126/SCIENCE.1207922
P407
P577
2011-09-01T00:00:00Z