Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
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Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localizationMammary stem cells, self-renewal pathways, and carcinogenesisGli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activationTamoxifen Resistance: Emerging Molecular TargetsTherapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem CellsAdvances in targeted and immunobased therapies for colorectal cancer in the genomic eraTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsTherapeutic Implications for Overcoming Radiation Resistance in Cancer TherapyThe Potential Role of Hedgehog Signaling in the Luminal/Basal Phenotype of Breast Epithelia and in Breast Cancer Invasion and MetastasisFucoxanthin and Its Metabolite Fucoxanthinol in Cancer Prevention and TreatmentCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsHedgehog signaling pathway in ovarian cancerPrognostic and clinicopathological value of Gli-1 expression in gastric cancer: A meta-analysisMolecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsHedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cellsFOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast CancerTargeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.Pathway-based classification of cancer subtypes.Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.Signalling pathways implicated in early mammary gland morphogenesis and breast cancer.Gli-1 siRNA induced apoptosis in Huh7 cells.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival.Quantitative diagnosis of breast tumors by morphometric classification of microenvironmental myoepithelial cells using a machine learning approach.Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer.Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancerMammary development and breast cancer: the role of stem cellsPathway-based analysis of breast cancer.Hedgehog signaling in the normal and neoplastic mammary gland.Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Semi-quantitative evaluation of CD44(+) /CD24(-) tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohistochemical staining method.Expression of Gli1 and Wnt2B correlates with progression and clinical outcome of pancreatic cancer.Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastasesFrequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.Will cancer stem cells provide new therapeutic targets?Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis.Regulator of G-protein signaling - 5 (RGS5) is a novel repressor of hedgehog signaling.
P2860
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P2860
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
@en
type
label
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
@en
prefLabel
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
@en
P2093
P1433
P1476
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer.
@en
P2093
Akira Tasaki
Hiroshi Nakashima
Makoto Kubo
Masafumi Nakamura
Masatoshi Nomura
Mitsuo Katano
Naoki Yamanaka
Syoji Kuroki
P304
P356
10.1158/0008-5472.CAN-04-0416
P407
P577
2004-09-01T00:00:00Z